Licodione

Base Information

Chemical Name:Licodione
CAS No.:61153-76-2
Molecular Formula:C₁₅H₁₂O₅
Molecular Weight:272.257
Hs Code.:2914501900
DSSTox Substance ID:DTXSID10210052
Nikkaji Number:J18.305I
Wikidata:Q27102842
Metabolomics Workbench ID:26871
Mol file:61153-76-2.mol

Synonyms:licodione

Suppliers and Price of Licodione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Licodione

Chemical Property:

Vapor Pressure:1.5E-13mmHg at 25°C
Boiling Point:569°C at 760 mmHg
PKA:7.42±0.35(Predicted)
Flash Point:312°C
PSA：94.83000
Density:1.416g/cm³
LogP:2.25910
XLogP3:2.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:272.06847348
Heavy Atom Count:20
Complexity:359

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)CC(=O)C2=C(C=C(C=C2)O)O)O

Technology Process of Licodione

There total 7 articles about Licodione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 76690-68-1
1-(2-hydroxy-4-benzyloxyphenyl)-3-(4-benzyloxyphenyl)-1,3-propanedione

: 61153-76-2
1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-1,3-propanedione

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; 2-methoxy-ethanol;
DOI:10.1016/S0031-9422(00)82219-0

Reference yield:

: 120-47-8
Ethyl 4-hydroxybenzoate

: 61153-76-2
1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-1,3-propanedione

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) K₂CO₃, KI; 2.) NaOH / 1.) DMF

2: SOCl₂ / dimethylformamide / 0.5 h / 60 °C

3: K₂CO₃ / acetone / 9 h / Heating

4: 0.34 g / H₂ / Pd/C / ethanol; 2-methoxy-ethanol

With sodium hydroxide; thionyl chloride; hydrogen; potassium carbonate; potassium iodide; palladium on activated charcoal; In ethanol; 2-methoxy-ethanol; N,N-dimethyl-formamide; acetone;
DOI:10.1016/S0031-9422(00)82219-0

Reference yield:

: 1486-51-7
p-(benzyloxy)benzoic acid

: 61153-76-2
1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-1,3-propanedione

Guidance literature:: Multi-step reaction with 3 steps

1: SOCl₂ / dimethylformamide / 0.5 h / 60 °C

2: K₂CO₃ / acetone / 9 h / Heating

3: 0.34 g / H₂ / Pd/C / ethanol; 2-methoxy-ethanol

With thionyl chloride; hydrogen; potassium carbonate; palladium on activated charcoal; In ethanol; 2-methoxy-ethanol; N,N-dimethyl-formamide; acetone;
DOI:10.1016/S0031-9422(00)82219-0