8H-Purin-8-one, 2-chloro-7,9-dihydro-7-methyl-9-phenyl-

Base Information

Chemical Name:8H-Purin-8-one, 2-chloro-7,9-dihydro-7-methyl-9-phenyl-
CAS No.:89743-87-3
Molecular Formula:C12H9ClN4O
Molecular Weight:260.67900
Hs Code.:

Synonyms:8H-Purin-8-one,2-chloro-7,9-dihydro-7-methyl-9-phenyl;2-chloro-7-methyl-9-phenyl-8,9-dihydro-purin-8-one;

Suppliers and Price of 8H-Purin-8-one, 2-chloro-7,9-dihydro-7-methyl-9-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 8H-Purin-8-one, 2-chloro-7,9-dihydro-7-methyl-9-phenyl-

Chemical Property:

PSA：52.71000
LogP:1.77260

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 8H-Purin-8-one, 2-chloro-7,9-dihydro-7-methyl-9-phenyl-

There total 5 articles about 8H-Purin-8-one, 2-chloro-7,9-dihydro-7-methyl-9-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 89660-30-0
2-chloro-9-phenyl-7,9-dihydro-8H-purin-8-one

: 74-88-4
methyl iodide

: 89743-87-3
2-chloro-7-methyl-9-phenyl-7,9-dihydro-8H-purin-8-one

Guidance literature:: 2-chloro-9-phenyl-7,9-dihydro-8H-purin-8-one; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 0.5h;

methyl iodide; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 1h;
DOI:10.1021/acs.jmedchem.9b01684

Reference yield: 93.0%

: 89660-30-0
2-chloro-9-phenyl-7,9-dihydro-8H-purin-8-one

: 77-78-1
dimethyl sulfate

: 89743-87-3
2-chloro-7-methyl-9-phenyl-7,9-dihydro-8H-purin-8-one

Guidance literature:: With potassium carbonate; In methanol; for 2h; Heating;

Reference yield:

: 54748-09-3
2-chloro-5-nitro-N-phenylpyrimidin-4-amine

: 89743-87-3
2-chloro-7-methyl-9-phenyl-7,9-dihydro-8H-purin-8-one

Guidance literature:: Multi-step reaction with 3 steps

1: 77 percent / H₂ / PtO₂ / aq. ethanol / 760 Torr / Ambient temperature

2: 49 percent / CHCl₃ / 5 h / Heating

3: 93 percent / K₂CO₃ / methanol / 2 h / Heating

With hydrogen; potassium carbonate; platinum(IV) oxide; In methanol; ethanol; chloroform;