4-Methyl-N-{[2-(2-nitrophenoxy)phenyl]methyl}benzene-1-sulfonamide

Base Information

Chemical Name:4-Methyl-N-{[2-(2-nitrophenoxy)phenyl]methyl}benzene-1-sulfonamide
CAS No.:89914-09-0
Molecular Formula:C20H18N2O5S
Molecular Weight:398.439
Hs Code.:
DSSTox Substance ID:DTXSID80522038
Wikidata:Q82386960

Synonyms:89914-09-0;DTXSID80522038;4-Methyl-N-{[2-(2-nitrophenoxy)phenyl]methyl}benzene-1-sulfonamide

Suppliers and Price of 4-Methyl-N-{[2-(2-nitrophenoxy)phenyl]methyl}benzene-1-sulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4-Methyl-N-{[2-(2-nitrophenoxy)phenyl]methyl}benzene-1-sulfonamide

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:398.09364285
Heavy Atom Count:28
Complexity:607

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)NCC2=CC=CC=C2OC3=CC=CC=C3[N+](=O)[O-]

Technology Process of 4-Methyl-N-{[2-(2-nitrophenoxy)phenyl]methyl}benzene-1-sulfonamide

There total 3 articles about 4-Methyl-N-{[2-(2-nitrophenoxy)phenyl]methyl}benzene-1-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 98-59-9
p-toluenesulfonyl chloride

: 2-aminomethyl-2'-nitrodiphenyl ether hydrochloride

: 89914-09-0
2-tosylaminomethyl-2'-nitrodiphenyl ether

Guidance literature:: With pyridine; for 24h;

Reference yield:

: 54106-40-0
1-methyl-2-(2-nitrophenoxy)benzene

: 89914-09-0
2-tosylaminomethyl-2'-nitrodiphenyl ether

Guidance literature:: Multi-step reaction with 3 steps

1: 59.8 percent / N-bromosuccinimide (NBS), benzoyl perchloride / CCl₄ / 30 h / Heating

2: 1.) urotropine, 2.) HCl / 1.) chloroform, reflux, 3 h, 2.) methanol, reflux, 2 h

3: 71 percent / pyridine / 24 h

With pyridine; hydrogenchloride; N-Bromosuccinimide; hexamethylenetetramine; pentachlorobenzoyl chloride; In tetrachloromethane;

Reference yield:

: 89914-07-8
2-bromomethyl-2'-nitrodiphenyl ether

: 89914-09-0
2-tosylaminomethyl-2'-nitrodiphenyl ether

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) urotropine, 2.) HCl / 1.) chloroform, reflux, 3 h, 2.) methanol, reflux, 2 h

2: 71 percent / pyridine / 24 h

With pyridine; hydrogenchloride; hexamethylenetetramine;