5H-Pyrido[3,2-b]pyrrolizin-5-one

Base Information

• Chemical Name: 5H-Pyrido[3,2-b]pyrrolizin-5-one
• CAS No.: 89991-18-4
• Molecular Formula: C10H6N2O
• Molecular Weight: 170.16700
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID80523429
• Nikkaji Number: J2.903.182G
• Wikidata: Q82389511
• Mol file: 89991-18-4.mol

Synonyms:5H-Pyrido[3,2-b]pyrrolizin-5-one;89991-18-4;PYRIDO[3,2-B]PYRROLIZIN-5-ONE;DTXSID80523429

Chemical Property of 5H-Pyrido[3,2-b]pyrrolizin-5-one

Chemical Property:

• PSA: 34.89000
• LogP: 1.41670
• Storage Temp.: 2-8°C
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 170.048012819
• Heavy Atom Count: 13
• Complexity: 241

Purity/Quality:

≥99% ^*data from raw suppliers

5H-Pyrido[3,2-b]pyrrolizin-5-one 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(N=C1)N3C=CC=C3C2=O

Technology Process of 5H-Pyrido[3,2-b]pyrrolizin-5-one

There total 6 articles about 5H-Pyrido[3,2-b]pyrrolizin-5-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

3-(pyrrolidin-1-yl)-2-(1H-pyrrol-1-yl)pyridine → 5H-pyrido[3,2-b]pyrrolizin-5-one (89991-18-4)

Guidance literature:

3-(pyrrolidin-1-yl)-2-(1H-pyrrol-1-yl)pyridine; With trichlorophosphate; at 70 ℃; for 18h;

With sodium hydroxide; In water; at 20 ℃; for 0.5h;

DOI:10.1016/j.ejmech.2018.09.017

Reference yield: 83.0%

cis,trans-2,5-dimethoxytetrahydrofuran (696-59-3) + 2-aminopyridin-3-carboxylic acid (5345-47-1) → 5H-pyrido[3,2-b]pyrrolizin-5-one (89991-18-4)

Guidance literature:

With 4-chlorpyridine hydrochloride; In 1,4-dioxane; for 24h; Reflux;

DOI:10.1016/j.tetlet.2011.08.139

Reference yield: 77.0%

2-(1H-pyrrol-1-yl)pyridine-3-carboxylic acid (154014-05-8) → 5H-pyrido[3,2-b]pyrrolizin-5-one (89991-18-4)

Guidance literature:

With bis(trichloromethyl) carbonate; In toluene; for 24h; Inert atmosphere; Reflux;

DOI:10.1016/j.tetlet.2010.10.060

upstream raw materials:

(2-chloropyrid-3-yl) (1H-pyrrol-2-yl)methanone

2-(1H-pyrrol-1-yl)pyridine-3-carboxylic acid

cis,trans-2,5-dimethoxytetrahydrofuran

2-aminopyridin-3-carboxylic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 89991-18-4 5H-Pyrido[3,2-b]pyrrolizin-5-one

Send

Send

Metric Ton KG G Pound L ML

Send

Send