4-Cyclobutyl-1-(4-nitrophenyl)-1H-pyrazole

Base Information

Chemical Name:4-Cyclobutyl-1-(4-nitrophenyl)-1H-pyrazole
CAS No.:90253-24-0
Molecular Formula:C₁₃H₁₃N₃O₂
Molecular Weight:243.265
Hs Code.:
DSSTox Substance ID:DTXSID10524005
Wikidata:Q82390548

Synonyms:4-Cyclobutyl-1-(4-nitrophenyl)-1H-pyrazole;90253-24-0;DTXSID10524005

Suppliers and Price of 4-Cyclobutyl-1-(4-nitrophenyl)-1H-pyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Cyclobutyl-1-(4-nitrophenyl)-1H-pyrazole

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:243.100776666
Heavy Atom Count:18
Complexity:306

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(C1)C2=CN(N=C2)C3=CC=C(C=C3)[N+](=O)[O-]

Technology Process of 4-Cyclobutyl-1-(4-nitrophenyl)-1H-pyrazole

There total 5 articles about 4-Cyclobutyl-1-(4-nitrophenyl)-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 51007-73-9
Cyclobutylmalonaldehyd

: 100-16-3
4-nitrophenylhydrazone

: 90253-24-0
4-Cyclobutyl-1-(4-nitrophenyl)pyrazol

Guidance literature:: With hydrogenchloride; In ethanol; for 0.333333h; Heating;

Reference yield:

: 51007-66-0,51007-78-4
1-Cyclobutyl-2-ethoxyethylen

: 90253-24-0
4-Cyclobutyl-1-(4-nitrophenyl)pyrazol

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) oxalyl chloride / 1.) 1,2-dichloroethane, 5 deg C; 2.) RT, 30 min; 40-50 deg C, 45 min; 70 deg C, 15 min

2: 1.) NaOH; 2.) 1N HCl / 1.) CH₃OH, H₂O, 70 deg C, 45 min; 2.) 5 min

3: 64 percent / conc. HCl / ethanol / 0.33 h / Heating

With hydrogenchloride; sodium hydroxide; oxalyl dichloride; In ethanol;

Reference yield:

: 51007-69-3
2-Cyclobutyl-3-(dimethylamino)-2-propenal

: 90253-24-0
4-Cyclobutyl-1-(4-nitrophenyl)pyrazol

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaOH; 2.) 1N HCl / 1.) CH₃OH, H₂O, 70 deg C, 45 min; 2.) 5 min

2: 64 percent / conc. HCl / ethanol / 0.33 h / Heating

With hydrogenchloride; sodium hydroxide; In ethanol;