4-Ethoxy-3-hydroxybenzoic acid

Base Information

Chemical Name:4-Ethoxy-3-hydroxybenzoic acid
CAS No.:90536-50-8
Molecular Formula:C9H10O4
Molecular Weight:182.176
Hs Code.:
European Community (EC) Number:860-406-6
DSSTox Substance ID:DTXSID80540570
Nikkaji Number:J1.695.249D
Wikidata:Q82416614

Synonyms:4-Ethoxy-3-hydroxybenzoic acid;90536-50-8;SCHEMBL825367;DTXSID80540570;EN300-188235;Z1255400792

Suppliers and Price of 4-Ethoxy-3-hydroxybenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
4-Ethoxy-3-hydroxybenzoicacid
500mg
$ 835.00

Total 1 raw suppliers

Chemical Property of 4-Ethoxy-3-hydroxybenzoic acid

Chemical Property:

Melting Point:218-219 °C
Boiling Point:351.7±27.0 °C(Predicted)
PSA：66.76000
Density:1.292±0.06 g/cm3(Predicted)
LogP:1.48910
XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:182.05790880
Heavy Atom Count:13
Complexity:181

Purity/Quality:

99% ^*data from raw suppliers

4-Ethoxy-3-hydroxybenzoicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=C(C=C(C=C1)C(=O)O)O

Technology Process of 4-Ethoxy-3-hydroxybenzoic acid

There total 2 articles about 4-Ethoxy-3-hydroxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2539-53-9
4-ethoxy-3-hydroxybenzaldehyde

: 3535-30-6
4-ethoxy-3-methoxybenzoic acid

: 99-50-3
3,4-Dihydroxybenzoic acid

: 90536-50-8
4-ethoxy-3-hydroxy-benzoic acid

Guidance literature:: With hydrogen bromide; Reaktion ueber mehrere Stufen;

Reference yield:

: 90536-50-8
4-ethoxy-3-hydroxy-benzoic acid

Guidance literature:: aus 3-Hydroxy-4-aethoxy-benzaldehyd;
DOI:10.1021/jo01068a001

Reference yield:

: 90536-50-8
4-ethoxy-3-hydroxy-benzoic acid

: 438570-13-9
{3-[2-(2,4-dichloro-phenyl)-ethoxy]-4-ethoxy-phenyl}-(4-pyridin-4-ylmethyl-piperazin-1-yl)-methanone

Guidance literature:: Multi-step reaction with 4 steps

1: HCl

2: DEAD; PPh₃-polystyrene / tetrahydrofuran / 16 h / 20 °C

3: aq. NaOH / dioxane / 1 h / 60 °C

4: TOTU; N-ethylmorpholine / dimethylformamide

With N-ethylmorpholine;; hydrogenchloride; sodium hydroxide; O-[(ethoxycarbonyl)cyanomethyleneamino]-N,N,N',N'-tetramethyluronium tetrafluoroborate; PPh₃-polystyrene; diethylazodicarboxylate; In tetrahydrofuran; 1,4-dioxane; N,N-dimethyl-formamide; 2: Mitsunobu reaction;
DOI:10.1021/jm049187l