11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 17-acetate

Base Information

Chemical Name:11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 17-acetate
CAS No.:16463-74-4
Molecular Formula:C₂₃H₃₂O₆
Molecular Weight:404.503
Hs Code.:
European Community (EC) Number:240-510-2
UNII:FHE0KL4PT1
DSSTox Substance ID:DTXSID60167784
Nikkaji Number:J318.198G
Wikidata:Q83037242
Mol file:16463-74-4.mol

Synonyms:16463-74-4;Hydrocortisone 17-Acetate;hydrocortisone-17-acetate;11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 17-acetate;FHE0KL4PT1;EINECS 240-510-2;[(8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate;Pregn-4-ene-3,20-dione, 17-(acetyloxy)-11,21-dihydroxy-, (11beta)-;Cortisol 17-Acetate;UNII-FHE0KL4PT1;SCHEMBL321463;DTXSID60167784;HDEDWNHZBWFQCB-JZYPGELDSA-N;AKOS030241133;HYDROCORTISONE IMPURITY J [EP IMPURITY];J-010155;17-(Acetyloxy)-11beta,21-dihydroxypregn-4-ene-3,20-dione;(11beta)-17-(Acetyloxy)-11,21-dihydroxypregn-4-ene-3,20-dione;11.BETA.,21-DIHYDROXY-3,20-DIOXOPREGN-4-EN-17-YL ACETATE;11.BETA.,17,21-TRIHYDROXYPREGN-4-ENE-3,20-DIONE 17-ACETATE;[11-Hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]acetate;Pregn-4-ene-3,20-dione, 17-(acetyloxy)-11,21-dihydroxy-, (11?)-;Cortisol, 17-acetate (7CI,8CI);(11?)-17-(Acetyloxy)-11,21-dihydroxypregn-4-ene-3,20-dione;Hydrocortisone 17-acetate

Suppliers and Price of 11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 17-acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Hydrocortisone17-Acetate
500mg
$ 1455.00

TRC
Hydrocortisone17-Acetate
50mg
$ 185.00

Total 14 raw suppliers

Chemical Property of 11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 17-acetate

Chemical Property:

Melting Point:234-237 °C
Boiling Point:566.6°Cat760mmHg
PKA:12.98±0.10(Predicted)
Flash Point:192.2°C
PSA：100.90000
Density:1.26g/cm³
LogP:2.35240
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:404.21988874
Heavy Atom Count:29
Complexity:786

Purity/Quality:

97% ^*data from raw suppliers

Hydrocortisone17-Acetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OC1(CCC2C1(CC(C3C2CCC4=CC(=O)CCC34C)O)C)C(=O)CO
Isomeric SMILES:CC(=O)O[C@@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C)C(=O)CO
Uses Hydrocortisone 17-Acetate (Hydrocortisone EP Impurity J) is a glucocorticoid and minor degradation product of Hydrocortisone 21-Acetate (H714620). Hydrocortisone 17-Acetate is a glucocorticoid and minor degradation product of Hydrocortisone 21-Acetate

Technology Process of 11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 17-acetate

There total 7 articles about 11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 17-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: