Benzoic acid, 4-[[(2-naphthalenylmethyl)amino]methyl]-, methyl ester

Base Information

Chemical Name:Benzoic acid, 4-[[(2-naphthalenylmethyl)amino]methyl]-, methyl ester
CAS No.:905818-73-7
Molecular Formula:C20H19NO2
Molecular Weight:305.376
Hs Code.:
DSSTox Substance ID:DTXSID40468807
Wikidata:Q82296227

Synonyms:905818-73-7;Benzoic acid, 4-[[(2-naphthalenylmethyl)amino]methyl]-, methyl ester;DTXSID40468807

Suppliers and Price of Benzoic acid, 4-[[(2-naphthalenylmethyl)amino]methyl]-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzoic acid, 4-[[(2-naphthalenylmethyl)amino]methyl]-, methyl ester

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:305.141578849
Heavy Atom Count:23
Complexity:376

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC=C(C=C1)CNCC2=CC3=CC=CC=C3C=C2

Technology Process of Benzoic acid, 4-[[(2-naphthalenylmethyl)amino]methyl]-, methyl ester

There total 1 articles about Benzoic acid, 4-[[(2-naphthalenylmethyl)amino]methyl]-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.6%

: 6232-11-7
methyl 4-(aminomethyl)benzoate hydrochloride

: 66-99-9
β-naphthaldehyde

: 905818-73-7
methyl 4-{[(2-naphthylmethyl)amino]methyl}benzoate

Guidance literature:: With sodium tetrahydroborate; triethylamine; In dichloromethane; at 20 ℃; for 6h;
DOI:10.1016/j.ejmech.2006.02.002

Reference yield: 39.7%

: 905818-73-7
methyl 4-{[(2-naphthylmethyl)amino]methyl}benzoate

: 540-51-2
2-bromoethanol

: 905818-77-1
methyl 4-{[(2-hydroxyethyl)(2-naphthylmethyl)amino]methyl}benzoate

Guidance literature:: With potassium carbonate; In acetonitrile; at 60 ℃;
DOI:10.1016/j.ejmech.2006.02.002

Reference yield:

: 905818-73-7
methyl 4-{[(2-naphthylmethyl)amino]methyl}benzoate

: K-182

Guidance literature:: Multi-step reaction with 2 steps

1: 39.7 percent / K₂CO₃ / acetonitrile / 60 °C

2: 27.6 percent / NH₂OH; KOH / methanol / 5 h / 20 °C

With potassium hydroxide; hydroxylamine; potassium carbonate; In methanol; acetonitrile;
DOI:10.1016/j.ejmech.2006.02.002