2-Bromoethanol is combustible.
Colorless to dark brown liquid. Sweet burning taste.
Irritant to eyes and mucous membranes.
Ethylene bromohydrin is mixed with a combustible solvent and burned in a chemicalincinerator.
Ethylene bromohydrin is not used much forany commercial purpose. The risk of expo sure to this compound arises when ethyleneoxide reacts with hydrobromic acid.
The vapors of ethylene bromohydrin are anirritant to the eyes and mucous membranes.It is corrosive to the skin. Ingestion of thiscompound can produce moderate to severetoxic effects. The target organs are the CNS,gastrointestinal tract, and liver. The lethaldose in mice by the intraperitoneal route was80 mg/kg.Ethylene bromohydrin manifested car cinogenicity in test animals. It caused tumorsin lungs and the gastrointestinal tract in micefrom intraperitoneal (150 mg/kg/8 weeks)and oral (43 mg/kg/80 weeks) dosages,respectively. It is a mutagen, positive to thehistidine reversion–Ames test.
intraperitoneal route. Questionable
carcinogen with experimental neoplastigenic
and tumorigenic data. Mutation data
reported. When heated to decomposition it
emits toxic fumes of Br-. See also
2-Bromoethanol forms an azeotrope with water; hydrolysis of aqueous solutions is accelerated by heat, alkalis and acids.
2-Bromoethanol is used in selective reduction of nitroarenes (PcFe(II)/NaBH4/2-bromoethanol catalyst system).
Air & Water Reactions
Hygroscopic. Water soluble.