Benzamide, N-(2-nitrophenyl)-4-[[(phenylmethyl)amino]methyl]-

Base Information

Chemical Name:Benzamide, N-(2-nitrophenyl)-4-[[(phenylmethyl)amino]methyl]-
CAS No.:905818-85-1
Molecular Formula:C21H19N3O3
Molecular Weight:361.4
Hs Code.:
DSSTox Substance ID:DTXSID70468032

Synonyms:905818-85-1;Benzamide, N-(2-nitrophenyl)-4-[[(phenylmethyl)amino]methyl]-;DTXSID70468032

Suppliers and Price of Benzamide, N-(2-nitrophenyl)-4-[[(phenylmethyl)amino]methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Benzamide, N-(2-nitrophenyl)-4-[[(phenylmethyl)amino]methyl]-

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:361.14264148
Heavy Atom Count:27
Complexity:480

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CNCC2=CC=C(C=C2)C(=O)NC3=CC=CC=C3[N+](=O)[O-]

Technology Process of Benzamide, N-(2-nitrophenyl)-4-[[(phenylmethyl)amino]methyl]-

There total 4 articles about Benzamide, N-(2-nitrophenyl)-4-[[(phenylmethyl)amino]methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.6%

: 4-(aminomethyl)-N-(2-nitorophenyl)benzamide hydrochloride

: 100-52-7
benzaldehyde

: 905818-85-1
4-[(benzylamino)methyl]-N-(2-nitrophenyl)benzamide

Guidance literature:: With sodium cyanoborohydride; acetic acid; triethylamine; In methanol; at 20 ℃; for 6h;
DOI:10.1016/j.ejmech.2006.02.002

Reference yield:

: 905818-80-6
tert-butyl 4-[(2-nitroanilino)carbonyl]benzylcarbamate

: 905818-85-1
4-[(benzylamino)methyl]-N-(2-nitrophenyl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / aq. HCl / methanol / 13 h / 20 °C

2: 51.6 percent / Et₃N; AcOH; NaBH₃CN / methanol / 6 h / 20 °C

With hydrogenchloride; sodium cyanoborohydride; acetic acid; triethylamine; In methanol;
DOI:10.1016/j.ejmech.2006.02.002

Reference yield:

: 33233-67-9
4-(tert-Butoxycarbonylaminomethyl)benzoic acid

: 905818-85-1
4-[(benzylamino)methyl]-N-(2-nitrophenyl)benzamide

Guidance literature:: Multi-step reaction with 4 steps

1: 100 percent / oxalyl chloride; pyridine / toluene; dimethylformamide / 6 h / 20 °C

2: 58 percent / pyridine / 13 h / 20 °C

3: 99 percent / aq. HCl / methanol / 13 h / 20 °C

4: 51.6 percent / Et₃N; AcOH; NaBH₃CN / methanol / 6 h / 20 °C

With pyridine; hydrogenchloride; oxalyl dichloride; sodium cyanoborohydride; acetic acid; triethylamine; In methanol; N,N-dimethyl-formamide; toluene;
DOI:10.1016/j.ejmech.2006.02.002