Ethyl 2-(1,3-dioxoisoindolin-2-yl)acetate

Base Information

Chemical Name:Ethyl 2-(1,3-dioxoisoindolin-2-yl)acetate
CAS No.:6974-10-3
Molecular Formula:C12H11 N O4
Molecular Weight:233.224
Hs Code.:2925190090
NSC Number:255094,23179
UNII:DCV2ZHH9RJ
DSSTox Substance ID:DTXSID40989906
Nikkaji Number:J955.050J
Wikidata:Q82979185
ChEMBL ID:CHEMBL1871113
Mol file:6974-10-3.mol

Synonyms:6974-10-3;Ethyl 2-(1,3-dioxoisoindolin-2-yl)acetate;ethyl 2-(1,3-dioxoisoindol-2-yl)acetate;Ethyl (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetate;2H-Isoindole-2-acetic acid, 1,3-dihydro-1,3-dioxo-, ethyl ester;NSC-23179;NSC-255094;phthalimidoacetic acid ethyl ester;Ethyl 1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetate;ethyl 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)acetate;Ethyl phthalimidoacetate;Phthalylglycine ethyl ester;amylsalicylate;2H-Isoindole-2-acetic acid,3-dihydro-1,3-dioxo-, ethyl ester;2H-Isoindole-2-aceticacid,1,3-dihydro-1,3-dioxo-,ethyl ester;N-(Ethoxycarbonylmethyl)phthalimide;DCV2ZHH9RJ;MLS000062962;CHEMBL1871113;SCHEMBL11453331;DTXSID40989906;HMS2359C08;Phthalimidoacetic acid, ethyl ester;NSC23179;MFCD00023083;NSC 23179;NSC255094;STK246956;AKOS000672240;Ethyl 1,3-dioxo-2-isoindolineacetate;NSC 255094;SB38365;SDCCGMLS-0019580.P002;LS-04303;SMR000071649;Ethyl2-(1,3-dioxoisoindolin-2-yl)acetate;CS-0206699;FT-0720717;A844957;A914678;AF-960/00453010;SR-01000510368;2-(1,3-dioxo-2-isoindolyl)acetic acid ethyl ester;2-Isoindolineacetic acid, 1,3-dioxo-, ethyl ester;SR-01000510368-1;ethyl (2,3-dihydro-1,3-dioxo-1h-isoindol-2-yl)acetate;ethyl 2-[1,3-bis(oxidanylidene)isoindol-2-yl]ethanoate;Ethyl (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-acetate;Ethyl (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetate #

Suppliers and Price of Ethyl 2-(1,3-dioxoisoindolin-2-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl2-(1,3-dioxoisoindol-2-yl)acetate
1g
$ 110.00

TRC
Ethyl2-(1,3-dioxoisoindol-2-yl)acetate
250mg
$ 50.00

Matrix Scientific
Ethyl (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-acetate
5g
$ 380.00

Matrix Scientific
Ethyl (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-acetate
500mg
$ 118.00

Matrix Scientific
Ethyl (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-acetate
1g
$ 181.00

J&W Pharmlab
2-Ethoxycarbonyl-methyl-phthalimide 97%
5g
$ 280.00

Crysdot
Ethyl2-(1,3-dioxoisoindolin-2-yl)acetate 95+%
1g
$ 182.00

Crysdot
Ethyl2-(1,3-dioxoisoindolin-2-yl)acetate 95+%
5g
$ 547.00

Chemenu
Ethyl2-(1,3-dioxoisoindolin-2-yl)acetate 95%
5g
$ 511.00

Atlantic Research Chemicals
Ethyl2-(1,3-Dioxoisoindolin-2-yl)acetate 95%
250mgs:
$ 28.28

Total 11 raw suppliers

Chemical Property of Ethyl 2-(1,3-dioxoisoindolin-2-yl)acetate

Chemical Property:

Vapor Pressure:0.00115mmHg at 25°C
Melting Point:112.5°C
Refractive Index:1.5560 (estimate)
Boiling Point:300°C at 760 mmHg
PKA:-2.47±0.20(Predicted)
Flash Point:170.2°C
PSA：63.68000
Density:1.32g/cm³
LogP:0.78360
Storage Temp.:2-8°C
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:233.06880783
Heavy Atom Count:17
Complexity:328

Purity/Quality:

99%, ^*data from raw suppliers

Ethyl2-(1,3-dioxoisoindol-2-yl)acetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CN1C(=O)C2=CC=CC=C2C1=O

Technology Process of Ethyl 2-(1,3-dioxoisoindolin-2-yl)acetate

There total 4 articles about Ethyl 2-(1,3-dioxoisoindolin-2-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 637-81-0
ethyl-2-azidoacetate

: 85-44-9
phthalic anhydride

: 6974-10-3
phthalimidoacetic acid ethyl ester

Guidance literature:: With triphenylphosphine; tetra-n-butylammonium cyanide; In benzene; for 12h; Ambient temperature;
DOI:10.1016/S0040-4039(00)84061-7

Reference yield: 60.0%

: 38846-64-9
2-ethynylbenzaldehyde

: 459-73-4
GlyOEt*HCl

: 6974-10-3
phthalimidoacetic acid ethyl ester

Guidance literature:: 2-ethynylbenzaldehyde; With [bis(acetoxy)iodo]benzene; water; sodium hydrogencarbonate; for 1h; Green chemistry;

GlyOEt*HCl; at 20 ℃; for 10h; Green chemistry;
DOI:10.1039/c5ra21932a