n-(4-Amino-2-methylquinolin-6-yl)butanamide

Base Information

Chemical Name:n-(4-Amino-2-methylquinolin-6-yl)butanamide
CAS No.:6954-99-0
Molecular Formula:C₁₄H₁₇N₃O
Molecular Weight:243.308
Hs Code.:
NSC Number:33341
DSSTox Substance ID:DTXSID00283775
Nikkaji Number:J457.383H
Wikidata:Q82018466
ChEMBL ID:CHEMBL420794

Synonyms:CHEMBL420794;6954-99-0;n-(4-amino-2-methylquinolin-6-yl)butanamide;NSC33341;SCHEMBL8358236;DTXSID00283775;BDBM50229895;NSC-33341;FT-0731411

Suppliers and Price of n-(4-Amino-2-methylquinolin-6-yl)butanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of n-(4-Amino-2-methylquinolin-6-yl)butanamide

Chemical Property:

Vapor Pressure:1.2E-10mmHg at 25°C
Boiling Point:513.3°Cat760mmHg
Flash Point:264.2°C
Density:1.207g/cm³
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:243.137162174
Heavy Atom Count:18
Complexity:295

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCC(=O)NC1=CC2=C(C=C(N=C2C=C1)C)N

Technology Process of n-(4-Amino-2-methylquinolin-6-yl)butanamide

There total 3 articles about n-(4-Amino-2-methylquinolin-6-yl)butanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5443-31-2
2-methyl-quinoline-4,6-diamine

: 141-75-3
butyryl chloride

: 6954-99-0
N-(4-amino-2-methyl-[6]quinolyl)-butyramide

Guidance literature:: With acetic acid;
DOI:10.1021/ja01596a041

Reference yield:

: 100795-23-1
N-(4-methoxy-2-methyl-6-quinolyl)acetamide

: 6954-99-0
N-(4-amino-2-methyl-[6]quinolyl)-butyramide

Guidance literature:: Multi-step reaction with 2 steps

1: 2.) HCl / 1.) from 135 deg C to 140 deg C, 2.) 90 deg C

2: glacial acetic acid / 1 h / Ambient temperature

With hydrogenchloride; acetic acid;
DOI:10.1021/jm00080a008