N-(4-methoxy-2-methylquinolin-6-yl)acetamide

Base Information Edit

Chemical Name:N-(4-methoxy-2-methylquinolin-6-yl)acetamide
CAS No.:100795-23-1
Molecular Formula:C13H14N2O2
Molecular Weight:230.26200
Hs Code.:2933499090
DSSTox Substance ID:DTXSID60406544
Wikidata:Q82211558
Mol file:100795-23-1.mol

Synonyms:N-(4-methoxy-2-methylquinolin-6-yl)acetamide;100795-23-1;N-(4-methoxy-2-methyl-6-quinolinyl)Acetamide;Acetamide, N-(4-methoxy-2-methyl-6-quinolinyl)-;SCHEMBL3738216;6-acetamido-4-methoxyquinaldine;DTXSID60406544;QEJJTUPQGGEUFD-UHFFFAOYSA-N;MFCD06681161;AKOS022889752;6-acetamido-4methoxy-2-methylquinoline;SB69059;SS-4676;6-acetamido-4-methoxy-2-methyl-quinoline;FT-0710337;N-(4-methoxy-2-methyl-6-quinolyl)acetamide;C90352;Z89270867

Suppliers and Price of N-(4-methoxy-2-methylquinolin-6-yl)acetamide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(4-Methoxy-2-methyl-6-quinolinyl)acetamide
1g
$ 835.00

SynQuest Laboratories
N-(4-Methoxy-2-methylquinolin-6-yl)acetamide
1 g
$ 400.00

Matrix Scientific
N-(4-Methoxy-2-methylquinolin-6-yl)acetamide >97%
1g
$ 521.00

Matrix Scientific
N-(4-Methoxy-2-methylquinolin-6-yl)acetamide >97%
500mg
$ 387.00

Crysdot
N-(4-Methoxy-2-methylquinolin-6-yl)acetamide 95+%
1g
$ 323.00

Chemenu
N-(4-Methoxy-2-methylquinolin-6-yl)acetamide 95%
1g
$ 305.00

Apolloscientific
N-(4-Methoxy-2-methylquinolin-6-yl)acetamide
1g
$ 338.00

AK Scientific
N-(4-Methoxy-2-methylquinolin-6-yl)acetamide
1g
$ 753.00

AK Scientific
N-(4-Methoxy-2-methylquinolin-6-yl)acetamide
500mg
$ 572.00

Total 2 raw suppliers

Chemical Property of N-(4-methoxy-2-methylquinolin-6-yl)acetamide Edit

Chemical Property:

PSA：51.22000
LogP:2.58320
Solubility.:Ethyl Acetate; Methanol
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:230.105527694
Heavy Atom Count:17
Complexity:283

Purity/Quality:

98%min ^*data from raw suppliers

N-(4-Methoxy-2-methyl-6-quinolinyl)acetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C2C=C(C=CC2=N1)NC(=O)C)OC
Uses N-(4-Methoxy-2-methyl-6-quinolinyl)acetamide is an intermediate in the synthesis of NSC 23766 (N900280), which is a highly soluble and membrane permeable Rac GTPase inhibitor. NSC 23766 inhibits Rac GTPase by targeting Rac activation by guanine nucleotide exchange factor (GEF). NSC 23766 has been shown to inhibit the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells.

Technology Process of N-(4-methoxy-2-methylquinolin-6-yl)acetamide

There total 9 articles about N-(4-methoxy-2-methylquinolin-6-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1140-81-4
N-(4-hydroxy-2-methylquinolin-6-yl)acetamide

: 77-78-1
dimethyl sulfate

: 100795-23-1
N-(4-methoxy-2-methyl-6-quinolyl)acetamide

Guidance literature:: N-(4-hydroxy-2-methylquinolin-6-yl)acetamide; dimethyl sulfate; In toluene; for 6h; Heating / reflux;

With sodium hydroxide; In water; pH=14;