1-Pyrrolidinecarboxylic acid, 3-[[cyclopropyl(phenylacetyl)amino]methyl]-4-[[[4-methoxy-3-(3-methoxy propoxy)benzoyl](1-methylethyl)amino]methyl]-, 1,1-dimethylethyl ester, (3R,4R)-

Base Information

Chemical Name:1-Pyrrolidinecarboxylic acid, 3-[[cyclopropyl(phenylacetyl)amino]methyl]-4-[[[4-methoxy-3-(3-methoxy propoxy)benzoyl](1-methylethyl)amino]methyl]-, 1,1-dimethylethyl ester, (3R,4R)-
CAS No.:911113-40-1
Molecular Formula:C37H53N3O7
Molecular Weight:651.844
Hs Code.:

1-Pyrrolidinecarboxylic acid,
3-[[cyclopropyl(phenylacetyl)amino]methyl]-4-[[[4-methoxy-3-(3-methoxy
propoxy)benzoyl](1-methylethyl)amino]methyl]-, 1,1-dimethylethyl ester,
(3R,4R)-

Synonyms:

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Chemical Property of 1-Pyrrolidinecarboxylic acid, 3-[[cyclopropyl(phenylacetyl)amino]methyl]-4-[[[4-methoxy-3-(3-methoxy propoxy)benzoyl](1-methylethyl)amino]methyl]-, 1,1-dimethylethyl ester, (3R,4R)-

Chemical Property:

Purity/Quality:

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Technology Process of 1-Pyrrolidinecarboxylic acid, 3-[[cyclopropyl(phenylacetyl)amino]methyl]-4-[[[4-methoxy-3-(3-methoxy propoxy)benzoyl](1-methylethyl)amino]methyl]-, 1,1-dimethylethyl ester, (3R,4R)-

There total 2 articles about 1-Pyrrolidinecarboxylic acid, 3-[[cyclopropyl(phenylacetyl)amino]methyl]-4-[[[4-methoxy-3-(3-methoxy propoxy)benzoyl](1-methylethyl)amino]methyl]-, 1,1-dimethylethyl ester, (3R,4R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 103-82-2
phenylacetic acid

: 911113-42-3
(3R,4R)-3-cyclopropylaminomethyl-4-({isopropyl-[4-methoxy-3-(3-methoxy-propoxy)-benzoyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

: 911113-40-1
(3R,4R)-3-[(cyclopropyl-phenylacetyl-amino)-methyl]-4-({isopropyl-[4-methoxy-3-(3-methoxy-propoxy)-benzoyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane;

Reference yield:

: 895245-15-5
(3S,4R)-3-formyl-4-({isopropyl-[4-methoxy-3-(3-methoxy-propoxy)-benzoyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

: 911113-40-1
(3R,4R)-3-[(cyclopropyl-phenylacetyl-amino)-methyl]-4-({isopropyl-[4-methoxy-3-(3-methoxy-propoxy)-benzoyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: methanol; acetic acid / 1 h / 20 °C

1.2: 1 h

2.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / dichloromethane

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In methanol; dichloromethane; acetic acid;