1-Pyrrolidinecarboxylic acid, 3-[(cyclopropylamino)methyl]-4-[[[4-methoxy-3-(3-methoxypropoxy)benz oyl](1-methylethyl)amino]methyl]-, 1,1-dimethylethyl ester, (3R,4R)-

Base Information

Chemical Name:1-Pyrrolidinecarboxylic acid, 3-[(cyclopropylamino)methyl]-4-[[[4-methoxy-3-(3-methoxypropoxy)benz oyl](1-methylethyl)amino]methyl]-, 1,1-dimethylethyl ester, (3R,4R)-
CAS No.:911113-42-3
Molecular Formula:C29H47N3O6
Molecular Weight:533.709
Hs Code.:

1-Pyrrolidinecarboxylic acid,
3-[(cyclopropylamino)methyl]-4-[[[4-methoxy-3-(3-methoxypropoxy)benz
oyl](1-methylethyl)amino]methyl]-, 1,1-dimethylethyl ester, (3R,4R)-

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Chemical Property of 1-Pyrrolidinecarboxylic acid, 3-[(cyclopropylamino)methyl]-4-[[[4-methoxy-3-(3-methoxypropoxy)benz oyl](1-methylethyl)amino]methyl]-, 1,1-dimethylethyl ester, (3R,4R)-

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Technology Process of 1-Pyrrolidinecarboxylic acid, 3-[(cyclopropylamino)methyl]-4-[[[4-methoxy-3-(3-methoxypropoxy)benz oyl](1-methylethyl)amino]methyl]-, 1,1-dimethylethyl ester, (3R,4R)-

There total 1 articles about 1-Pyrrolidinecarboxylic acid, 3-[(cyclopropylamino)methyl]-4-[[[4-methoxy-3-(3-methoxypropoxy)benz oyl](1-methylethyl)amino]methyl]-, 1,1-dimethylethyl ester, (3R,4R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 895245-15-5
(3S,4R)-3-formyl-4-({isopropyl-[4-methoxy-3-(3-methoxy-propoxy)-benzoyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

: 765-30-0
Cyclopropylamine

: 911113-42-3
(3R,4R)-3-cyclopropylaminomethyl-4-({isopropyl-[4-methoxy-3-(3-methoxy-propoxy)-benzoyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

Guidance literature:: (3S,4R)-3-formyl-4-({isopropyl-[4-methoxy-3-(3-methoxy-propoxy)-benzoyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester; Cyclopropylamine; In methanol; acetic acid; at 20 ℃; for 1h;

With sodium tetrahydroborate; In methanol; acetic acid; for 1h;

Reference yield:

: 103-82-2
phenylacetic acid

: 911113-42-3
(3R,4R)-3-cyclopropylaminomethyl-4-({isopropyl-[4-methoxy-3-(3-methoxy-propoxy)-benzoyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

: 911113-40-1
(3R,4R)-3-[(cyclopropyl-phenylacetyl-amino)-methyl]-4-({isopropyl-[4-methoxy-3-(3-methoxy-propoxy)-benzoyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane;