2,4-Dinitro-m-toluidine

Base Information

• Chemical Name: 2,4-Dinitro-m-toluidine
• CAS No.: 10202-92-3
• Molecular Formula: C7H7 N3 O4
• Molecular Weight: 197.15
• DSSTox Substance ID: DTXSID5074428
• Nikkaji Number: J154.054H
• Wikidata: Q82002780
• Mol file: 10202-92-3.mol

Synonyms:3-methyl-2,4-dinitroaniline;10202-92-3;2,4-Dinitro-m-toluidine;Benzenamine, 3-methyl-2,4-dinitro-;3-Amino-2,6-dinitrotoluene;m-Toluidine, 2,4-dinitro-;BRN 2653563;Benzenamine, 2,4-dinitro-3-methyl-;2,4-Dinitro-3-methylaniline;2-12-00-00480 (Beilstein Handbook Reference);SCHEMBL2006430;DTXSID5074428;AC2711;MFCD01679549;AKOS037629572;SY039091;LS-154363;A919995

Chemical Property of 2,4-Dinitro-m-toluidine

Chemical Property:

• Vapor Pressure: 3.53E-06mmHg at 25°C
• Boiling Point: 386.5°Cat760mmHg
• Flash Point: 187.5°C
• Density: 1.497g/cm³
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 197.04365571
• Heavy Atom Count: 14
• Complexity: 246

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=CC(=C1[N+](=O)[O-])N)[N+](=O)[O-]

Technology Process of 2,4-Dinitro-m-toluidine

There total 8 articles about 2,4-Dinitro-m-toluidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

dimethyl sulfoxide (67-68-5,8070-53-9) + 2,4-Dinitroanilin (97-02-9) → 3-methyl-2,4-dinitroaniline (10202-92-3)

Guidance literature:

With potassium tert-butylate; at 20 ℃; for 6h;

DOI:10.1016/S0040-4039(00)01215-6

Reference yield: 10.0%

2,6-dinitrotoluene (606-20-2) → 3-methyl-2,4-dinitroaniline (10202-92-3)

Guidance literature:

With potassium permanganate; ammonia; at -33 ℃;

DOI:10.1023/B:RUJO.0000044545.10133.96

Reference yield:

2,4-dinitro-3-methylanisole (30366-26-8) → 3-methyl-2,4-dinitroaniline (10202-92-3)

Guidance literature:

With ethanol; ammonia; at 130 ℃;

upstream raw materials:

2,6-dinitrotoluene

2,4-dinitro-3-methylanisole

3-bromo-2,6-dinitro-toluene

ethanol

Downstream raw materials:

4-chloro-2-methyl-3-nitro-aniline

methyl 2-(4-(4-(2,4-dichlorophenylsulfonamido)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indazol-5-yloxy)-3-methoxyphenyl)acetate

2-(4-(4-(2,4-dichlorophenylsulfonamido)-1H-indazol-5-yloxy)-3-methoxyphenyl)acetic acid

methyl 2-(4-(4-amino-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indazol-5-yloxy)-3-methoxyphenyl)acetate

Refernces

• 1、 -. "COMPOUNDS AND METHODS USEFUL FOR TREATING ASTHMA AND ALLERGIC INFLAMMATION". Page/Page column 89-90. . Retrieved 2009/01/20.
• 2、 -. "2-IMIDAZOLINE, 2-OXAZOLINE, 2-THIAZOLINE, AND 4-IMIDAZOLE DERIVATIVES OF METHYLPHENYL, METHOXYPHENYL, AND AMINOPHENYL ALKYLSULFONAMIDES AND UREAS AND THEIR USE". . . Retrieved 2008/06/13.