2-(3-Hydroxyphenyl)-3-methyl-1-propyl-1H-indol-5-ol

Base Information

Chemical Name:2-(3-Hydroxyphenyl)-3-methyl-1-propyl-1H-indol-5-ol
CAS No.:91444-79-0
Molecular Formula:C18H19NO2
Molecular Weight:281.354
Hs Code.:
ChEMBL ID:CHEMBL285071
DSSTox Substance ID:DTXSID80539843
Wikidata:Q82415654

Synonyms:91444-79-0;2-(3-Hydroxyphenyl)-3-methyl-1-propyl-1H-indol-5-ol;CHEMBL285071;DTXSID80539843

Suppliers and Price of 2-(3-Hydroxyphenyl)-3-methyl-1-propyl-1H-indol-5-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-(3-Hydroxyphenyl)-3-methyl-1-propyl-1H-indol-5-ol

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:281.141578849
Heavy Atom Count:21
Complexity:348

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCN1C2=C(C=C(C=C2)O)C(=C1C3=CC(=CC=C3)O)C

Technology Process of 2-(3-Hydroxyphenyl)-3-methyl-1-propyl-1H-indol-5-ol

There total 4 articles about 2-(3-Hydroxyphenyl)-3-methyl-1-propyl-1H-indol-5-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 91444-46-1
5-Methoxy-2-(3-methoxy-phenyl)-3-methyl-1-propyl-1H-indole

: 91444-79-0
2-(3-Hydroxy-phenyl)-3-methyl-1-propyl-1H-indol-5-ol

Guidance literature:: With boron tribromide; In dichloromethane; at -60 - 20 ℃;
DOI:10.1021/jm00377a011

Reference yield:

: 21726-71-6
2-bromo-1-(3-methoxyphenyl)propan-1-one

: 91444-79-0
2-(3-Hydroxy-phenyl)-3-methyl-1-propyl-1H-indol-5-ol

Guidance literature:: Multi-step reaction with 3 steps

1: N,N-dimethylaniline / 170 °C

2: 1.) Na/liquid NH₃ / 1.) THF, -70 deg C, 30 min, 2.) THF, -70 deg C, 30 min

3: BBr₃ / CH₂Cl₂ / -60 - 20 °C

With ammonia; sodium; boron tribromide; N,N-dimethyl-aniline; In dichloromethane;
DOI:10.1021/jm00377a011

Reference yield:

: 104-94-9
4-methoxy-aniline

: 91444-79-0
2-(3-Hydroxy-phenyl)-3-methyl-1-propyl-1H-indol-5-ol

Guidance literature:: Multi-step reaction with 3 steps

1: N,N-dimethylaniline / 170 °C

2: 1.) Na/liquid NH₃ / 1.) THF, -70 deg C, 30 min, 2.) THF, -70 deg C, 30 min

3: BBr₃ / CH₂Cl₂ / -60 - 20 °C

With ammonia; sodium; boron tribromide; N,N-dimethyl-aniline; In dichloromethane;
DOI:10.1021/jm00377a011