16-Methylamino-3-methoxy-1,3,5-estratrien-17-ol

Base Information

Chemical Name:16-Methylamino-3-methoxy-1,3,5-estratrien-17-ol
CAS No.:90193-07-0
Molecular Formula:C₂₀H₂₉NO₂
Molecular Weight:315.456
Hs Code.:
DSSTox Substance ID:DTXSID501009242
Wikidata:Q83005990
Mol file:90193-07-0.mol

Synonyms:16-methylamino-3-methoxy-1,3,5-estratrien-17-ol;ent-16 alpha-methylamino-3-methoxy-1,3,5(10)-estratrien-17 beta-ol;MAMOET

Suppliers and Price of 16-Methylamino-3-methoxy-1,3,5-estratrien-17-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 16-Methylamino-3-methoxy-1,3,5-estratrien-17-ol

Chemical Property:

Vapor Pressure:2.18E-09mmHg at 25°C
Boiling Point:463.4°Cat760mmHg
Flash Point:234.1°C
PSA：41.49000
Density:1.14g/cm³
LogP:3.50100
XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:315.219829168
Heavy Atom Count:23
Complexity:441

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC3C(C1CC(C2O)NC)CCC4=C3C=CC(=C4)OC
Isomeric SMILES:C[C@]12CC[C@H]3[C@H]([C@@H]1C[C@H]([C@@H]2O)NC)CCC4=C3C=CC(=C4)OC

Technology Process of 16-Methylamino-3-methoxy-1,3,5-estratrien-17-ol

There total 4 articles about 16-Methylamino-3-methoxy-1,3,5-estratrien-17-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51946-36-2
16α-azido-3-methoxyestra-1,3,5(10)-triene-17β-ol

: 90193-07-0
16α-methylamino-3-methoxy-1,3,5(10)-estratrien-17β-ol

Guidance literature:: Multi-step reaction with 2 steps

1: LiAlH₄ / tetrahydrofuran / Heating

2: 1) Na, 2) LiAlH₄ / 1) EtOH, r.t., 2) THF, reflux

With lithium aluminium tetrahydride; sodium; In tetrahydrofuran;
DOI:10.1016/0039-128X(82)90002-2

Reference yield:

: ent-16α-azido-3-methoxy-1,3,5(10)-estratrien-17β-ol

: 90193-07-0
ent-16α-methylamino-3-methoxy-1,3,5(10)-estratrien-17β-ol

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / LiAlH₄ / tetrahydrofuran / 1 h / Heating

2: 1) Na, 2) LiAlH₄ / 1) EtOH, r.t., 2 h, 2) THF, reflux, 2.5 h

With lithium aluminium tetrahydride; sodium; In tetrahydrofuran;
DOI:10.1016/0039-128X(82)90002-2

Reference yield:

: 51946-46-4
16α-amino-17β-hydroxy-3-methoxy-estra-1,3,5(10)-triene

: 109-94-4
formic acid ethyl ester

: 90193-07-0
16α-methylamino-3-methoxy-1,3,5(10)-estratrien-17β-ol

Guidance literature:: With lithium aluminium tetrahydride; sodium; Multistep reaction; 1) EtOH, r.t., 2) THF, reflux;
DOI:10.1016/0039-128X(82)90002-2