Carbamic acid, ((cyclohexylamino)sulfonyl)-, 2-chloroethyl ester

Base Information

• Chemical Name: Carbamic acid, ((cyclohexylamino)sulfonyl)-, 2-chloroethyl ester
• CAS No.: 87708-08-5
• Molecular Formula: C9H17 Cl N2 O4 S
• Molecular Weight: 0
• Hs Code.: 2935009090
• DSSTox Substance ID: DTXSID00236584
• Wikidata: Q83118554
• Mol file: 87708-08-5.mol

Synonyms:BRN 4486967;2-Chloroethyl ((cyclohexylamino)sulfonyl)carbamate;87708-08-5;Carbamic acid, ((cyclohexylamino)sulfonyl)-, 2-chloroethyl ester;N-(Chloro-2 ethoxycarbonyl) N'-(cyclohexyl) sulfamide [French];N-(Chloro-2 ethoxycarbonyl) N'-(cyclohexyl) sulfamide;C9H17ClN2O4S;DTXSID00236584;C9-H17-Cl-N2-O4-S;LS-49204

Chemical Property of Carbamic acid, ((cyclohexylamino)sulfonyl)-, 2-chloroethyl ester

Chemical Property:

• PSA: 96.37000
• Density: 1.35g/cm³
• LogP: 2.79460
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 284.0597559
• Heavy Atom Count: 17
• Complexity: 335

Purity/Quality:

2-CHLOROETHYL ((CYCLOHEXYLAMINO)SULFONYL)CARBAMATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(CC1)NS(=O)(=O)NC(=O)OCCCl

Technology Process of Carbamic acid, ((cyclohexylamino)sulfonyl)-, 2-chloroethyl ester

There total 1 articles about Carbamic acid, ((cyclohexylamino)sulfonyl)-, 2-chloroethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2-chloroethyl chlorosulfonylcarbamate (87708-19-8) + cyclohexylamine (108-91-8,157973-60-9) → N-(chloro-2 ethoxycarbonyl) N'-(cyclohexyl) sulfamide (87708-08-5)

Guidance literature:

DOI:10.1016/S0040-4039(00)88103-4

Reference yield: 90.0%

N-(chloro-2 ethoxycarbonyl) N'-(cyclohexyl) sulfamide (87708-08-5) → N-(N'-cyclohexyl sulfamyl) oxazolidinone-2 (116943-65-8)

Guidance literature:

With triethylamine; In dichloromethane; for 15h;

Reference yield: 90.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + N-(chloro-2 ethoxycarbonyl) N'-(cyclohexyl) sulfamide (87708-08-5) → N-methyl N-(chloro-2 ethoxycarbonyl) N'-(cyclohexyl) sulfamide (116943-75-0)

Guidance literature:

In diethyl ether; dichloromethane;

upstream raw materials:

2-chloroethyl chlorosulfonylcarbamate

cyclohexylamine

Downstream raw materials:

N-methyl N-(chloro-2 ethoxycarbonyl) N'-(cyclohexyl) sulfamide

N-(N'-cyclohexyl sulfamyl) oxazolidinone-2

Refernces

• 1、 Montero, Jean-Louis,Dewynter, Georges,Agoh, Bernadette,Delaunay, Barbara,Imbach, Jean-Louis. "SELECTIVE SYNTHESIS OF SULFONYLUREAS AND CARBOXYSULFAMIDES. A NOVEL ROUTE TO OXAZOLIDINES.". . p. 3091 - 3094. Retrieved 2007/10/02.