8-Hydrazinoadenosine

Base Information

Chemical Name:8-Hydrazinoadenosine
CAS No.:3868-34-6
Molecular Formula:C10H15N7O4
Molecular Weight:297.2706
Hs Code.:
Wikidata:Q76423790
Mol file:3868-34-6.mol

Synonyms:8-hydrazinoadenosine;3868-34-6;2-(6-amino-8-hydrazinyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol;(2~{R},3~{R},4~{S},5~{R})-2-(6-azanyl-8-diazanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol;NEOMYCIN A;NEAMINE;SCHEMBL952636;DF8

Suppliers and Price of 8-Hydrazinoadenosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of 8-Hydrazinoadenosine

Chemical Property:

Vapor Pressure:1.48E-23mmHg at 25°C
Boiling Point:748.8°Cat760mmHg
Flash Point:406.7°C
Density:2.29g/cm³
XLogP3:-1.5
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:3
Exact Mass:297.11855199
Heavy Atom Count:21
Complexity:377

Purity/Quality:: 99.3% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=NC(=C2C(=N1)N(C(=N2)NN)C3C(C(C(O3)CO)O)O)N
Isomeric SMILES:C1=NC(=C2C(=N1)N(C(=N2)NN)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N

Technology Process of 8-Hydrazinoadenosine

There total 2 articles about 8-Hydrazinoadenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2946-39-6
8-bromoadenosine

: 3868-34-6
8-hydrazinoadenosine

Guidance literature:: With hydrazine; In ethanol; Inert atmosphere; Reflux;
DOI:10.1021/acs.jmedchem.5b00279

Reference yield:

: 3868-34-6
8-hydrazinoadenosine

Guidance literature:: 8-Bromadenosin,Hydrazin;
DOI:10.1055/s-1977-24555

Reference yield:

: 3868-34-6
8-hydrazinoadenosine

: C₂₁H₂₆N₁₀O₁₄P₂

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydrogenchloride; isopentyl nitrite / Inert atmosphere

2.1: trichlorophosphate; trimethyl phosphite / Inert atmosphere

2.2: pH 7 / Inert atmosphere

3.1: pyridine; diisopropyl-carbodiimide / water / 144 h / 20 °C / Inert atmosphere

With pyridine; trimethyl phosphite; hydrogenchloride; diisopropyl-carbodiimide; trichlorophosphate; isopentyl nitrite; In water;
DOI:10.1021/acs.jmedchem.5b00279