8-Bromoadenosine

Base Information

Chemical Name:8-Bromoadenosine
CAS No.:2946-39-6
Molecular Formula:C10H12BrN5O4
Molecular Weight:346.14
Hs Code.:2934 99 90
European Community (EC) Number:220-959-0
UNII:85C9T4TXH2
DSSTox Substance ID:DTXSID001021364
Nikkaji Number:J136.591F
Wikidata:Q27105621
Metabolomics Workbench ID:68040
ChEMBL ID:CHEMBL1775009
Mol file:2946-39-6.mol

Synonyms:8-bromoadenosine

Suppliers and Price of 8-Bromoadenosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
8-Bromoadenosine
1g
$ 368.00

Usbiological
8-Bromoadenosine
1g
$ 315.00

TRC
8-BromoAdenosine
1g
$ 45.00

Sigma-Aldrich
8-Bromoadenosine powder
1g
$ 182.00

Sigma-Aldrich
8-Bromoadenosine powder
5g
$ 646.00

Medical Isotopes, Inc.
8-Bromoadenosine
5 g
$ 1640.00

Medical Isotopes, Inc.
8-Bromoadenosine
1 g
$ 830.00

Matrix Scientific
(2R,3R,4S,5R)-2-(6-Amino-8-bromo-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol 95+%
10g
$ 756.00

Matrix Scientific
(2R,3R,4S,5R)-2-(6-Amino-8-bromo-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol 95+%
1g
$ 181.00

Matrix Scientific
(2R,3R,4S,5R)-2-(6-Amino-8-bromo-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol 95+%
5g
$ 471.00

Total 67 raw suppliers

Chemical Property of 8-Bromoadenosine

Chemical Property:

Appearance/Colour:Off-White Solid
Vapor Pressure:1.29E-21mmHg at 25°C
Melting Point:210-212 °C(dec.)(lit.)
Refractive Index:1.94
Boiling Point:717.7 °C at 760 mmHg
PKA:12.89±0.70(Predicted)
Flash Point:387.8 °C
PSA：139.54000
Density:2.45 g/cm³
LogP:-0.63630
Storage Temp.:2-8°C
Sensitive.:Air Sensitive
Solubility.:DMSO (Slightly), Methanol (Slightly, Sonicated)
Water Solubility.:Soluble in DMSO, and DMF. Insoluble in water.
XLogP3:0
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:2
Exact Mass:345.00727
Heavy Atom Count:20
Complexity:367

Purity/Quality:

99% ^*data from raw suppliers

8-Bromoadenosine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36-24/25-22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=NC(=C2C(=N1)N(C(=N2)Br)C3C(C(C(O3)CO)O)O)N
Isomeric SMILES:C1=NC(=C2C(=N1)N(C(=N2)Br)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N
Description 8-Bromoadenosine is a nucleotide that is structurally related to adenosine. It can be used as an inhibitor of guanine nucleotide-binding proteins and has shown biological properties in vitro. 8-Bromoadenosine has been shown to inhibit the mitochondrial membrane potential, cytosolic Ca2+, and the synthesis of RNA and protein. 8-Bromoadenosine also inhibits leukemia inhibitory factor (LIF) production by 3T3-L1 preadipocytes and induces apoptosis in T84 cells.
Uses 8-Bromoadenosine is an adenosine binding inhibitor. formation of 8-S-L-cysteinyladenosine from 8-Bromoadenosine and cysteine.

Technology Process of 8-Bromoadenosine

There total 8 articles about 8-Bromoadenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%