Technology Process of Benzenamine,
4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-2-(2,2,2-trifluoroethoxy)-
There total 3 articles about Benzenamine,
4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-2-(2,2,2-trifluoroethoxy)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium dithionite; sodium hydrogencarbonate;
tetra(n-butyl)ammonium hydrogensulfate;
In
tert-butyl methyl ether; water;
at 20 ℃;
for 12h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: hydrogen / palladium 10% on activated carbon / methanol / 3 h / 20 °C
2: sodium dithionite; sodium hydrogencarbonate / tetra(n-butyl)ammonium hydrogensulfate / tert-butyl methyl ether; water / 12 h / 20 °C
With
sodium dithionite; hydrogen; sodium hydrogencarbonate;
palladium 10% on activated carbon; tetra(n-butyl)ammonium hydrogensulfate;
In
methanol; tert-butyl methyl ether; water;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 5 - 20 °C
1.2: 2 h / 20 °C
2.1: hydrogen / palladium 10% on activated carbon / methanol / 3 h / 20 °C
3.1: sodium dithionite; sodium hydrogencarbonate / tetra(n-butyl)ammonium hydrogensulfate / tert-butyl methyl ether; water / 12 h / 20 °C
With
sodium dithionite; hydrogen; sodium hydride; sodium hydrogencarbonate;
palladium 10% on activated carbon; tetra(n-butyl)ammonium hydrogensulfate;
In
methanol; tert-butyl methyl ether; water; N,N-dimethyl-formamide;
