2-(t-Butyloxycarbonyl)amino-4S-hydroxy-5S-(benzyloxycarbonyl)amino-1,6 -diphenyl-2-azahexane

Base Information

• Chemical Name: 2-(t-Butyloxycarbonyl)amino-4S-hydroxy-5S-(benzyloxycarbonyl)amino-1,6 -diphenyl-2-azahexane
• CAS No.: 150767-06-9
• Molecular Formula: C30H37 N3 O5
• Molecular Weight: 519.63
• Mol file: 150767-06-9.mol

Synonyms:Hydrazinecarboxylicacid,2-[2-hydroxy-4-phenyl-3-[[(phenylmethoxy)carbonyl]amino]butyl]-2-(phenylmethyl)-,1,1-dimethylethyl ester, [S-(R*,R*)]-

Chemical Property of 2-(t-Butyloxycarbonyl)amino-4S-hydroxy-5S-(benzyloxycarbonyl)amino-1,6 -diphenyl-2-azahexane

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 107.11000
• Density: 1.183g/cm³
• LogP: 5.23570

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(t-Butyloxycarbonyl)amino-4S-hydroxy-5S-(benzyloxycarbonyl)amino-1,6 -diphenyl-2-azahexane

There total 7 articles about 2-(t-Butyloxycarbonyl)amino-4S-hydroxy-5S-(benzyloxycarbonyl)amino-1,6 -diphenyl-2-azahexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-[2(S)-hydroxy-3(S)-amino-4-phenyl-butyl]-1-[phenylmethyl]-2-[tert-butoxycarbonyl]-hydrazine (149267-73-2) + potassium carbonate (584-08-7) + benzyl chloroformate (501-53-1,94274-21-2) → 1-[2(S)-Hydroxy-3(S)-(benzyloxycarbonylamino)-4-phenyl-butyl]-1-[phenylmethyl]-2-[tert-butoxycarbonyl]-hydrazine (150767-06-9)

Guidance literature:

With potassium hydrogensulfate; In 1,4-dioxane; hexane; water;

Reference yield:

threo N-Cbz-alanyl epoxide (159141-73-8) + N'-benzylhydrazinecarboxylic acid tert-butyl ester (53370-84-6) → 1-[2(S)-Hydroxy-3(S)-(benzyloxycarbonylamino)-4-phenyl-butyl]-1-[phenylmethyl]-2-[tert-butoxycarbonyl]-hydrazine (150767-06-9)

Guidance literature:

In tetrahydrofuran; methanol;

Reference yield:

(S)-2-(phenylmethoxycarbonyl)amino-1-phenylbut-3-ene (150767-05-8) → 1-[2(S)-Hydroxy-3(S)-(benzyloxycarbonylamino)-4-phenyl-butyl]-1-[phenylmethyl]-2-[tert-butoxycarbonyl]-hydrazine (150767-06-9)

Guidance literature:

Multi-step reaction with 2 steps

1: m-chloroperbenzoic acid (MCPBA) / CH₂Cl₂ / 0 °C

2: Al₂O₃

With aluminum oxide; 3-chloro-benzenecarboperoxoic acid; In dichloromethane;

DOI:10.1039/c39930001052

upstream raw materials:

(2R,2S)-(3S)-1,2-epoxy-3-phenylmethoxycarbonylamino-4-phenylbutane

N'-benzylhydrazinecarboxylic acid tert-butyl ester

t-butoxycarbonylhydrazine

t-butyl 3-benzylidenecarbazate

Downstream raw materials:

1-[2(S)-Hydroxy-3(S)-(benzyloxycarbonylamino)-4-phenyl-butyl]-1-[phenylmethyl]hydrazine

1-[2(S)-Hydroxy-3(S)-(N-(quinoline-2-carbonyl)-(L)-asparaginyl)amino-4-phenyl-butyl]1-[phenylmethyl]-2-[tert-butoxycarbonyl]-hydrazine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 150767-06-9 2-(t-Butyloxycarbonyl)amino-4S-hydroxy-5S-(benzyloxycarbonyl)amino-1,6 -diphenyl-2-azahexane

Send

Send

Metric Ton KG G Pound L ML

Send

Send