4-[2-Ethyl-4-(4-fluorophenyl)-1,3-thiazol-5-yl]-2-fluoropyridine

Base Information

Chemical Name:4-[2-Ethyl-4-(4-fluorophenyl)-1,3-thiazol-5-yl]-2-fluoropyridine
CAS No.:917807-95-5
Molecular Formula:C16H12F2N2S
Molecular Weight:
Hs Code.:
DSSTox Substance ID:DTXSID70575513
Wikidata:Q82464871

Synonyms:917807-95-5;4-[2-Ethyl-4-(4-fluorophenyl)-1,3-thiazol-5-yl]-2-fluoropyridine;SCHEMBL2798070;DTXSID70575513;CGBYZCRWMHLJRP-UHFFFAOYSA-N;2-fluoro-4-[2-ethyl-4-(4-fluorophenyl)-1,3-thiazol-5-yl]pyridine

Suppliers and Price of 4-[2-Ethyl-4-(4-fluorophenyl)-1,3-thiazol-5-yl]-2-fluoropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of 4-[2-Ethyl-4-(4-fluorophenyl)-1,3-thiazol-5-yl]-2-fluoropyridine

Chemical Property:

XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:302.06892589
Heavy Atom Count:21
Complexity:336

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=NC(=C(S1)C2=CC(=NC=C2)F)C3=CC=C(C=C3)F

Technology Process of 4-[2-Ethyl-4-(4-fluorophenyl)-1,3-thiazol-5-yl]-2-fluoropyridine

There total 1 articles about 4-[2-Ethyl-4-(4-fluorophenyl)-1,3-thiazol-5-yl]-2-fluoropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 917807-95-5
2-fluoro-4-[2-ethyl-4-(4-fluorophenyl)-1,3-thiazol-5-yl]pyridine

Guidance literature:

Reference yield: 77.0%

: 917807-95-5
2-fluoro-4-[2-ethyl-4-(4-fluorophenyl)-1,3-thiazol-5-yl]pyridine

: 765-30-0
Cyclopropylamine

: 1231880-73-1
N-cyclopropyl-4-[2-ethyl-4-(4-fluorophenyl)-1,3-thiazol-5-yl]pyridine-2-amine

Guidance literature:: at 150 ℃; for 16h; In closed vessel;

Reference yield:

: 917807-95-5
2-fluoro-4-[2-ethyl-4-(4-fluorophenyl)-1,3-thiazol-5-yl]pyridine

: 1231880-81-1
N-Cyclopropyl-N-{4-[2-ethyl-4-(4-fluorophenyl)-1,3-thiazol-5-yl]pyridin-2-yl}acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 16 h / 150 °C / In closed vessel

2: potassium carbonate / acetonitrile / 40 °C

With potassium carbonate; In acetonitrile;