ETHYL 2,3-DIBROMO-3-PHENYLPROPIONATE

Base Information

• Chemical Name: ETHYL 2,3-DIBROMO-3-PHENYLPROPIONATE
• CAS No.: 5464-70-0
• Molecular Formula: C11H12Br2O2
• Molecular Weight: 336.023
• Hs Code.: 29420000
• Mol file: 5464-70-0.mol

Synonyms:Hydrocinnamicacid, a,b-dibromo-, ethyl ester (6CI,7CI,8CI);Ethyl2,3-dibromo-3-phenylpropionate;Ethyl a,b-dibromo-b-phenylpropionate;Ethyl a,b-dibromodihydrocinnamate;NSC 15440;NSC 68516;Zebromal;

Chemical Property of ETHYL 2,3-DIBROMO-3-PHENYLPROPIONATE

Chemical Property:

• Vapor Pressure: 0.000388mmHg at 25°C
• Melting Point: 77-79 °C
• Refractive Index: 1.574
• Boiling Point: 317.3 °C at 760 mmHg
• Flash Point: 145.7 °C
• PSA: 26.30000
• Density: 1.657 g/cm³
• LogP: 3.44920
• Storage Temp.: Amber Vial, -20°C Freezer
• Solubility.: Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

ETHYL 2,3-DIBROMO-3-PHENYLPROPIONATE ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL 2,3-DIBROMO-3-PHENYLPROPIONATE

There total 17 articles about ETHYL 2,3-DIBROMO-3-PHENYLPROPIONATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

ethyl 3-phenyl-2-propenoate (103-36-6) → 2,3-dibromo-3-phenyl-propionic acid ethyl ester (5464-70-0)

Guidance literature:

With bromine; In various solvent(s); for 1h; Ambient temperature;

DOI:10.1080/00397919508012663

Reference yield: 94.0%

ethyl cinnamate (4192-77-2) → rac-(2S,3R)-ethyl 2,3-dibromo-3-phenylpropanoate (5464-70-0,30983-70-1,87439-83-6,99107-37-6,99570-22-6,99570-23-7,100227-07-4)

Guidance literature:

With oxone||potassium monopersulfate triple salt; potassium bromide; N-(n-butyl)-2-methylbenzamide; In dichloromethane; water; at 20 ℃; for 1h; Reagent/catalyst; diastereoselective reaction;

DOI:10.1039/c3cc49850f

Reference yield: 91.0%

ethyl cinnamate (4192-77-2) → 2,3-Dibromo-3-phenyl-propionic acid ethyl ester (5464-70-0,30983-70-1,87439-83-6,99107-37-6,99570-22-6,99570-23-7,100227-07-4)

Guidance literature:

With maghemite(γ-Fe₂O₃) nanoparticle supported 2,2'-bis[3-(triethoxysilyl)propyl]imidazolium substituted diethyl ether bis(tribromide); In methanol; dichloromethane; for 6h; Reflux;

DOI:10.1002/ejic.201300755

upstream raw materials:

ethyl 3-phenyl-2-propenoate

2,3-dibromo-3-phenylpropanoic acid

ethyl iodide

ethyl cinnamate

Downstream raw materials:

ethyl β-ethoxycinnamate

3-Phenyl-1-propanol

trans-5-phenyl-2,3,5,6-tetrahydro-imidazo[2,1-b]thiazole-6-carboxylic acid ethyl ester

cis-5-phenyl-2,3,5,6-tetrahydro-imidazo[2,1-b]thiazole-6-carboxylic acid ethyl ester