GBR12783 dihydrochloride

Base Information

• Chemical Name: GBR12783 dihydrochloride
• CAS No.: 67469-75-4
• Molecular Formula: C28H32N2O*2ClH
• Molecular Weight: 485.497
• DSSTox Substance ID: DTXSID1042572
• Mol file: 67469-75-4.mol

Synonyms:GBR12783 dihydrochloride;DTXSID1042572;SCHEMBL11369681;BCP18783;GBR-12783 dihydrochloride;GBR 12783 dihydrochloride

Chemical Property of GBR12783 dihydrochloride

Chemical Property:

• PSA: 15.71000
• LogP: 6.60340
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 9
• Exact Mass: 484.2048191
• Heavy Atom Count: 33
• Complexity: 477

Purity/Quality:

≥99% by HPLC ^*data from raw suppliers

GBR12783Dihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CN(CCN1CCOC(C2=CC=CC=C2)C3=CC=CC=C3)CC=CC4=CC=CC=C4.Cl.Cl
• Uses: GBR 12783 Dihydrochloride is a potent, selective dopamine uptake inhibitor.

Technology Process of GBR12783 dihydrochloride

There total 1 articles about GBR12783 dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

trans-1-cinnamylpiperazine (18903-01-0,114312-65-1,87179-40-6) + 1,1'-[(2-chloroethoxy)methylene]bis-benzene (32669-06-0) → GBR 12921 dihydrochloride (67469-75-4)

Guidance literature:

With hydrogenchloride; potassium carbonate; potassium iodide; In various solvent(s); for 24h; Heating;

upstream raw materials:

trans-1-cinnamylpiperazine

1,1'-[(2-chloroethoxy)methylene]bis-benzene

Refernces