3-[(3,5-dichlorobenzoyl)amino]-2-hydroxy-3-methylbutanoic acid

Base Information

Chemical Name:3-[(3,5-dichlorobenzoyl)amino]-2-hydroxy-3-methylbutanoic acid
CAS No.:31110-42-6
Molecular Formula:C12H13 Cl2 N O4
Molecular Weight:306.1419
Hs Code.:

Synonyms:Butyricacid, 3-(3,5-dichlorobenzamido)-2-hydroxy-3-methyl- (8CI); b-(3,5-Dichlorobenzamido)-a-hydroxy-b-methylbutyric acid

Suppliers and Price of 3-[(3,5-dichlorobenzoyl)amino]-2-hydroxy-3-methylbutanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-[(3,5-dichlorobenzoyl)amino]-2-hydroxy-3-methylbutanoic acid

Chemical Property:

Vapor Pressure:2.52E-10mmHg at 25°C
Boiling Point:487.7°Cat760mmHg
Flash Point:248.7°C
Density:1.442g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-[(3,5-dichlorobenzoyl)amino]-2-hydroxy-3-methylbutanoic acid

There total 3 articles about 3-[(3,5-dichlorobenzoyl)amino]-2-hydroxy-3-methylbutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 401520-42-1
N-(2-carbamoyl-2-hydroxy-1,1-dimethyl-ethyl)-3,5-dichloro-benzamide

: 31110-42-6
3-(3,5-dichloro-benzoylamino)-2-hydroxy-3-methylbutyric acid

Guidance literature:: With hydrogenchloride; sodium nitrite; In 1,4-dioxane; at 20 ℃;
DOI:10.1021/jf0107196

Reference yield:

: 2905-62-6
3,5-dichlorobenzoyl chloride

: 31110-42-6
3-(3,5-dichloro-benzoylamino)-2-hydroxy-3-methylbutyric acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: aq. NaOH / toluene / 2 h / 20 °C

1.2: NaOH / ethanol / 3 h / Heating

2.1: 68 percent / aq. HCl; NaNO₂ / dioxane / 20 °C

With hydrogenchloride; sodium hydroxide; sodium nitrite; In 1,4-dioxane; toluene;
DOI:10.1021/jf0107196

Reference yield:

: 3-amino-2-hydroxy-3-methylbutyramide hydrochloride

: 31110-42-6
3-(3,5-dichloro-benzoylamino)-2-hydroxy-3-methylbutyric acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: aq. NaOH / toluene / 2 h / 20 °C

1.2: NaOH / ethanol / 3 h / Heating

2.1: 68 percent / aq. HCl; NaNO₂ / dioxane / 20 °C

With hydrogenchloride; sodium hydroxide; sodium nitrite; In 1,4-dioxane; toluene;
DOI:10.1021/jf0107196