N-[(4-methoxyphenyl)sulfonyl]-D-alanine

Base Information

Chemical Name:N-[(4-methoxyphenyl)sulfonyl]-D-alanine
CAS No.:918330-60-6
Molecular Formula:C₁₀H₁₃NO₅S
Molecular Weight:259.283
Hs Code.:
DSSTox Substance ID:DTXSID60351641
Wikidata:Q27097799
Metabolomics Workbench ID:151724

Synonyms:N-[(4-methoxyphenyl)sulfonyl]-D-alanine;918330-60-6;(2R)-2-[(4-methoxyphenyl)sulfonylamino]propanoic acid;n-4'-methoxybenzenesulfonyl-d-alanine;SCHEMBL4618694;DTXSID60351641;AKOS017427177;DB08599;(R)-2-(4-Methoxyphenylsulfonamido)propanoic acid;Q27097799;Z829933094

Suppliers and Price of N-[(4-methoxyphenyl)sulfonyl]-D-alanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N-[(4-methoxyphenyl)sulfonyl]-D-alanine

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:259.05144369
Heavy Atom Count:17
Complexity:353

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)OC
Isomeric SMILES:C[C@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)OC

Technology Process of N-[(4-methoxyphenyl)sulfonyl]-D-alanine

There total 1 articles about N-[(4-methoxyphenyl)sulfonyl]-D-alanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 338-69-2,25191-17-7,18875-37-1
D-Alanine

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 918330-60-6
N-4'-methoxybenzenesulfonyl-D-alanine

Guidance literature:: With triethylamine; In 1,4-dioxane; water; Ambient temperature;
DOI:10.1021/jm960871c

Reference yield:

: 918330-60-6
N-4'-methoxybenzenesulfonyl-D-alanine

: 161315-02-2
2R-[[(4-methoxybenzene)sulfonyl](benzyl)amino]propionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: toluene / 3 h / 95 °C

2: K₂CO₃ / dimethylformamide / 48 h / Ambient temperature

3: HCl gas / CH₂Cl₂ / 4 h / Ambient temperature

With hydrogenchloride; potassium carbonate; In dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm960871c

Reference yield:

: 918330-60-6
N-4'-methoxybenzenesulfonyl-D-alanine

: N-hydroxy-2(R)-[[4-methoxybenzenesulfonyl](benzyl)amino]-propionamide

Guidance literature:: Multi-step reaction with 5 steps

1: toluene / 3 h / 95 °C

2: K₂CO₃ / dimethylformamide / 48 h / Ambient temperature

3: HCl gas / CH₂Cl₂ / 4 h / Ambient temperature

4: 1-hydroxybenzotriazole, 4-methylmorpholine, N-<(dimethylamino)propyl>-N'-ethylcarbodiimide*HCl / CH₂Cl₂

5: HCl gas / CH₂Cl₂; ethanol / 48 h / Ambient temperature

With 4-methyl-morpholine; hydrogenchloride; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In ethanol; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm960871c