Tilomisole

Base Information

Chemical Name:Tilomisole
CAS No.:58433-11-7
Molecular Formula:C17H11 Cl N2 O2 S
Molecular Weight:342.806
Hs Code.:
UNII:651G60U372
DSSTox Substance ID:DTXSID40207137
Nikkaji Number:J22.806K
Wikipedia:Tilomisole
Wikidata:Q6587418
NCI Thesaurus Code:C152631
ChEMBL ID:CHEMBL2104737
Mol file:58433-11-7.mol

Synonyms:3-(p-chlorophenyl)thiazolo(3,2-a)benzimidazole-2-acetic acid;NSC 310633;tilomisole;Wy 18251;Wy-18,251;Wy-18251

Suppliers and Price of Tilomisole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TILOMISOLE 95.00%
5MG
$ 502.81

Total 5 raw suppliers

Chemical Property of Tilomisole

Chemical Property:

PSA：82.84000
Density:1.51g/cm³
LogP:4.49650
XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:342.0229765
Heavy Atom Count:23
Complexity:458

Purity/Quality:

99% ^*data from raw suppliers

TILOMISOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)N=C3N2C(=C(S3)CC(=O)O)C4=CC=C(C=C4)Cl

Technology Process of Tilomisole

There total 12 articles about Tilomisole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 39481-06-6
[3-(4-chloro-phenyl)-3-hydroxy-2,3-dihydro-benzo[4,5]imidazo[2,1-b]thiazol-2-yl]-acetic acid; hydrobromide

: 58433-11-7
3-(p-chlorophenyl)-thiazolo[3,2-a]benzimidazole-2-acetic acid

Guidance literature:: With methanesulfonic acid; In water;

Reference yield: 40.0%

: 650-51-1
sodium trichloroacetate

: 3-(4-chlorophenyl)benzoimidazo[2,1-b]thiazole-2-carbaldehyde

: 58433-11-7
3-(p-chlorophenyl)-thiazolo[3,2-a]benzimidazole-2-acetic acid

Guidance literature:: sodium trichloroacetate; 3-(4-chlorophenyl)benzoimidazo[2,1-b]thiazole-2-carbaldehyde; In tert-butyl alcohol; at 35 ℃; for 8h;

With sodium tetrahydroborate; sodium hydroxide; In water; for 0.5h; pH=8 - 9;