7-Chloro-6-fluoroisoquinoline

Base Information

Chemical Name:7-Chloro-6-fluoroisoquinoline
CAS No.:918490-51-4
Molecular Formula:C9H5ClFN
Molecular Weight:181.59400
Hs Code.:2933992000
European Community (EC) Number:806-835-4
DSSTox Substance ID:DTXSID50697469
Wikidata:Q82627377
Mol file:918490-51-4.mol

Synonyms:7-CHLORO-6-FLUOROISOQUINOLINE;918490-51-4;7-Chloro-6-fluoro-isoquinoline;6-Fluoro-7-chloroisoquinoline;SCHEMBL1411933;6-Fluoro-7-chloro-isoquinoline;DTXSID50697469;BCZPUVXMWIBIRE-UHFFFAOYSA-N;MFCD11846299;AKOS026675655;SS-4666;EN300-113962;Z1255403762

Suppliers and Price of 7-Chloro-6-fluoroisoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-chloro-6-fluoroisoquinoline
50mg
$ 90.00

TRC
7-chloro-6-fluoroisoquinoline
25mg
$ 45.00

TRC
7-chloro-6-fluoroisoquinoline
250mg
$ 310.00

SynQuest Laboratories
7-Chloro-6-fluoroisoquinoline
1 g
$ 400.00

Matrix Scientific
7-Chloro-6-fluoroisoquinoline >95%
1g
$ 521.00

Matrix Scientific
7-Chloro-6-fluoroisoquinoline >95%
5g
$ 1302.00

Matrix Scientific
7-Chloro-6-fluoroisoquinoline >95%
500mg
$ 387.00

Labseeker
7-chloro-6-fluoroisoquinoline 95
1g
$ 2925.00

Crysdot
7-Chloro-6-fluoroisoquinoline 95+%
1g
$ 361.00

Crysdot
7-Chloro-6-fluoroisoquinoline 95+%
5g
$ 903.00

Total 1 raw suppliers

Chemical Property of 7-Chloro-6-fluoroisoquinoline

Chemical Property:

Boiling Point:296.0±20.0 °C(Predicted)
PKA:4.50±0.10(Predicted)
PSA：12.89000
Density:1.366±0.06 g/cm3(Predicted)
LogP:3.02730
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:181.0094550
Heavy Atom Count:12
Complexity:165

Purity/Quality:: 7-chloro-6-fluoroisoquinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=CC2=CC(=C(C=C21)F)Cl

Technology Process of 7-Chloro-6-fluoroisoquinoline

There total 5 articles about 7-Chloro-6-fluoroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1035922-63-4
N-[(3-chloro-4-fluoro-phenyl)methyl]-N-(2,2-dimethoxyethyl)-4-methyl-benzenesulfonamide

: 918490-51-4
7-chloro-6-fluoro-isoquinoline

Guidance literature:: N-[(3-chloro-4-fluoro-phenyl)methyl]-N-(2,2-dimethoxyethyl)-4-methyl-benzenesulfonamide; With aluminum (III) chloride; In dichloromethane; at 20 ℃;

With sodium hydroxide; water; In dichloromethane; at 0 ℃;

Reference yield:

: (E)-1-(3-chloro-4-fluoro-phenyl)-N-(2,2-dimethoxyethyl)methanimine

: 918490-51-4
7-chloro-6-fluoro-isoquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: sodium tetrahydroborate / ethanol / 2 h / 18 - 25 °C

2: pyridine / dichloromethane / 5 h / 0 - 25 °C

3: aluminum (III) chloride / dichloromethane / 12 h / 18 - 25 °C

With pyridine; aluminum (III) chloride; sodium tetrahydroborate; In ethanol; dichloromethane;

Reference yield:

: 1035922-61-2
N-[(3-chloro-4-fluoro-phenyl)methyl]-2,2-dimethoxy-ethanamine

: 918490-51-4
7-chloro-6-fluoro-isoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 5 h / 0 - 25 °C

2: aluminum (III) chloride / dichloromethane / 12 h / 18 - 25 °C

With pyridine; aluminum (III) chloride; In dichloromethane;