Phosphinic acid, P-(1-naphthalenylmethyl)-

Base Information

• Chemical Name: Phosphinic acid, P-(1-naphthalenylmethyl)-
• CAS No.: 918545-42-3
• Molecular Formula: C11H11O2P
• Molecular Weight: 206.181
• DSSTox Substance ID: DTXSID30478536
• Mol file: 918545-42-3.mol

Synonyms:Phosphinic acid, P-(1-naphthalenylmethyl)-;918545-42-3;SCHEMBL457044;DTXSID30478536

Chemical Property of Phosphinic acid, P-(1-naphthalenylmethyl)-

Chemical Property:

• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 205.04184156
• Heavy Atom Count: 14
• Complexity: 217

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC=C2C[P+](=O)O

Technology Process of Phosphinic acid, P-(1-naphthalenylmethyl)-

There total 1 articles about Phosphinic acid, P-(1-naphthalenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

1-Chloromethylnaphthalene (86-52-2) → tris(1-naphthylmethyl)phosphine oxide + bis(1-naphthylmethyl)phosphine oxide + [(naphthalen-1-yl)methyl]phosphinic acid (918545-42-3) + 1-Methylnaphthalene (90-12-0,34475-76-8)

Guidance literature:

With potassium hydroxide; hydrogen; phosphan; In water; dimethyl sulfoxide; at 85 - 90 ℃; for 2.5h; Further byproducts.;

DOI:10.1007/s11176-005-0291-1

Reference yield:

3-Phenylpropenol (104-54-1) + [(naphthalen-1-yl)methyl]phosphinic acid (918545-42-3) → C20H19O2P

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In tert-Amyl alcohol; at 102 ℃; for 24h; Inert atmosphere;

DOI:10.1021/ol8000415

upstream raw materials:

1-Chloromethylnaphthalene