Crystallise the alcohol from diethyl ether/pentane. [Beilstein 6 I 281.]
Cinnamyl alcohol was used to study the alkylation of 2,4-di-tert-butylphenol by cinnamyl alcohol using aluminum-containing mesoporous ethane-silica catalyst. It was used to study gold nanoparticles supported on titanium dioxide catalysed oxidative coupling of alcohols and amines to form the corresponding imines.
In perfumery; as deodorant in 12.5% solution in glycerol.
Cinnamyl alcohol occurs (in esterified form) in storax,
Myroxylon pereirae, cinnamon leaves, and hyacinth
oil. It is obtained by the alkaline hydrolysis of storax
and prepared synthetically by reducing cinnamal diacetate
with iron filings and acetic acid, and from cinnamaldehyde
by Meerwein-Ponndorf reduction with
aluminum isopropoxide. Cinnamic alcohol is contained
in the “fragrance mix.” As a fragrance allergen,
it has to be mentioned by name in cosmetics within the
EU. Occupational cases of contact dermatitis were
reported in perfume industry. Patch tests can be positive
in food handlers.
As an organic compound, Cinnamic alcohol has a very distinct sweet, spicy, hyacinth odour that is found in resins, balsams and cinnamon leaves. It is used commonly in the fragrance industry due to its distinctive odour, which can be applied as a deodorant, fragrance and additive in cosmetic products and in the formulation of bath products, body and hand products, such as soaps, toothpaste, deodorants, etc. Besides, it also finds application as a food additive in chewing gum, bakery products, candy and soft drinks. Naturally, Cinnamyl alcohol is occurrent only in small amount, thus its industrial demand is usually fulfilled by chemical synthesis starting from the reduction of cinnamaldehyde.
Cinnamyl alcohol has been found to have a sensitising effect on some particular people, thus it is also considered as a Standardized Chemical Allergen. The physiologic effect of cinnamyl alcohol is caused by the Increased Histamine Release and cell-mediated Immunity.
ChEBI: A primary alcohol comprising an allyl core with a hydroxy substituent at the 1-position and a phenyl substituent at the 3-position (geometry of the C2C bond unspecified).