3-acetyl-N-tert-butylbenzenesulfonamide

Base Information

Chemical Name:3-acetyl-N-tert-butylbenzenesulfonamide
CAS No.:918810-67-0
Molecular Formula:C12H17NO3S
Molecular Weight:255.338
Hs Code.:
DSSTox Substance ID:DTXSID40429155
Wikidata:Q82242101

Synonyms:3-acetyl-N-tert-butylbenzenesulfonamide;918810-67-0;SCHEMBL4598709;DTXSID40429155;FPSVXPQAPUVYAQ-UHFFFAOYSA-N;AKOS008939988

Suppliers and Price of 3-acetyl-N-tert-butylbenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-acetyl-N-tert-butylbenzenesulfonamide

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:255.09291458
Heavy Atom Count:17
Complexity:376

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C1=CC(=CC=C1)S(=O)(=O)NC(C)(C)C

Technology Process of 3-acetyl-N-tert-butylbenzenesulfonamide

There total 3 articles about 3-acetyl-N-tert-butylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 918810-66-9
3-(tert-butylsulfamoyl)-N-methoxy-N-methylbenzamide

: 75-16-1
methylmagnesium bromide

: 918810-67-0
3-acetyl-N-tert-butyl-benzenesulfonamide

Guidance literature:: In tetrahydrofuran; diethyl ether; at -78 - 20 ℃; for 24.3h;

Reference yield:

: 4025-64-3
3-Carboxybenzenesulfonyl chloride

: 918810-67-0
3-acetyl-N-tert-butyl-benzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: dichloromethane / 2.5 h / 0 - 20 °C

2: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / dichloromethane / 12 h / 20 °C

3: tetrahydrofuran / 12.33 h / -78 - 20 °C

With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; dichloromethane;

Reference yield:

: 222409-98-5
3-(tert-butylsulfamoyl)benzoic acid

: 918810-67-0
3-acetyl-N-tert-butyl-benzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / dichloromethane / 12 h / 20 °C

2: tetrahydrofuran / 12.33 h / -78 - 20 °C

With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; dichloromethane;