4-(4-Methoxyphenyl)but-3-yn-1-amine

Base Information

Chemical Name:4-(4-Methoxyphenyl)but-3-yn-1-amine
CAS No.:918871-63-3
Molecular Formula:C11H13NO
Molecular Weight:175.23
Hs Code.:
ChEMBL ID:CHEMBL3951751
DSSTox Substance ID:DTXSID50580983
Wikidata:Q82471993

Synonyms:4-(4-Methoxyphenyl)but-3-yn-1-amine;918871-63-3;SCHEMBL1443828;CHEMBL3951751;DTXSID50580983;BDBM185649;US9161922, Table 2, Compound?4

Suppliers and Price of 4-(4-Methoxyphenyl)but-3-yn-1-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 4-(4-Methoxyphenyl)but-3-yn-1-amine

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:175.099714038
Heavy Atom Count:13
Complexity:193

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C#CCCN

Technology Process of 4-(4-Methoxyphenyl)but-3-yn-1-amine

There total 3 articles about 4-(4-Methoxyphenyl)but-3-yn-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 87639-43-8
4-(4-methoxyphenyl)but-3-yn-1-yl 4-methylbenzenesulfonate

: 918871-63-3
C₁₁H₁₃NO

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 4 h / 90 °C / Inert atmosphere

2: hydrazine hydrate / toluene / 2 h / Reflux; Inert atmosphere

With hydrazine hydrate; In N,N-dimethyl-formamide; toluene;
DOI:10.1002/anie.201604986

Reference yield:

: 696-62-8
para-iodoanisole

: 918871-63-3
C₁₁H₁₃NO

Guidance literature:: Multi-step reaction with 4 steps

1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / Inert atmosphere

2: triethylamine / dichloromethane / 8 h / 0 - 20 °C / Inert atmosphere

3: N,N-dimethyl-formamide / 4 h / 90 °C / Inert atmosphere

4: hydrazine hydrate / toluene / 2 h / Reflux; Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; hydrazine hydrate; triethylamine; In dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1002/anie.201604986

Reference yield:

: 52999-15-2
4-(p-methoxyphenyl)-3-butyn-1-ol

: 918871-63-3
C₁₁H₁₃NO

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 8 h / 0 - 20 °C / Inert atmosphere

2: N,N-dimethyl-formamide / 4 h / 90 °C / Inert atmosphere

3: hydrazine hydrate / toluene / 2 h / Reflux; Inert atmosphere

With hydrazine hydrate; triethylamine; In dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1002/anie.201604986