N-cyclohexyl-1-(2,4-dichlorophenyl)-6-methyl-4H-indeno[1,2-c]pyrazole-3-carboxamide

Base Information

Chemical Name:N-cyclohexyl-1-(2,4-dichlorophenyl)-6-methyl-4H-indeno[1,2-c]pyrazole-3-carboxamide
CAS No.:919077-81-9
Molecular Formula:C₂₄H₂₃Cl₂N₃O
Molecular Weight:440.372
Hs Code.:
ChEMBL ID:CHEMBL216735
DSSTox Substance ID:DTXSID00582457
Nikkaji Number:J2.738.599K
Pharos Ligand ID:P8HDTFZJVMMB
Wikidata:Q27164324
Mol file:919077-81-9.mol

Synonyms:GP 2A;919077-81-9;CB2 receptor agonist 3;N-Cyclohexyl-1-(2,4-dichlorophenyl)-1,4-dihydro-6-methylindeno[1,2-c]pyrazole-3-carboxamide;GP2a;N-cyclohexyl-1-(2,4-dichlorophenyl)-6-methyl-4H-indeno[1,2-c]pyrazole-3-carboxamide;CHEMBL216735;GP-2A;GP2A;SCHEMBL17562960;CHEBI:92606;DTXSID00582457;EX-A594;HMS3269N05;HMS3413B06;HMS3677B06;BCP28791;BDBM50200166;AKOS024457237;NCGC00167828-01;MS-27909;HY-107471;CS-0028586;BRD-K34608650-001-01-6;Q27164324;1-(2'',4''-dichlorophenyl)-6-methyl-N-cyclohexylamine-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide;N-Cyclohexyl-1-(2,4-dichlorophenyl)-6-methyl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide

Suppliers and Price of N-cyclohexyl-1-(2,4-dichlorophenyl)-6-methyl-4H-indeno[1,2-c]pyrazole-3-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
GP2A
10mg
$ 185.00

Tocris
GP2a ≥99%(HPLC)
50
$ 794.00

Tocris
GP2a ≥99%(HPLC)
10
$ 199.00

Total 10 raw suppliers

Chemical Property of N-cyclohexyl-1-(2,4-dichlorophenyl)-6-methyl-4H-indeno[1,2-c]pyrazole-3-carboxamide

Chemical Property:

Vapor Pressure:6.33E-16mmHg at 25°C
Boiling Point:632.9oC at 760 mmHg
Flash Point:336.6oC
PSA：46.92000
Density:1.41g/cm3
LogP:6.51210
Storage Temp.:Store at RT
XLogP3:6.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:439.1218178
Heavy Atom Count:30
Complexity:628

Purity/Quality:

97% ^*data from raw suppliers

GP2A ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(C=C1)C3=C(C2)C(=NN3C4=C(C=C(C=C4)Cl)Cl)C(=O)NC5CCCCC5
Uses GP 2A is a selective CB2 agonist that also shows modest agonism at CB1 receptors.

Technology Process of N-cyclohexyl-1-(2,4-dichlorophenyl)-6-methyl-4H-indeno[1,2-c]pyrazole-3-carboxamide

There total 2 articles about N-cyclohexyl-1-(2,4-dichlorophenyl)-6-methyl-4H-indeno[1,2-c]pyrazole-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 511533-14-5
1-(2',4'-dichlorophenyl)-6-methyl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxylic acid

: 919077-81-9
NESS₄₀₀

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / toluene / 3 h / Heating

2: 0.17 g / CH₂Cl₂ / 3 h / 20 °C

With thionyl chloride; In dichloromethane; toluene;
DOI:10.1021/jm060920d