Benzoic acid, 2,3-bis(2-propen-1-yloxy)-, methyl ester

Base Information

• Chemical Name: Benzoic acid, 2,3-bis(2-propen-1-yloxy)-, methyl ester
• CAS No.: 919123-45-8
• Molecular Formula: C14H16O4
• Molecular Weight: 248.279
• Mol file: 919123-45-8.mol

Synonyms:2,3-bis-allyloxy-benzoic acid methyl ester;methyl 2,3-bis(allyloxy)benzoate;Benzoic acid,2,3-bis(2-propen-1-yloxy)-,methyl ester;

Chemical Property of Benzoic acid, 2,3-bis(2-propen-1-yloxy)-, methyl ester

Chemical Property:

• PSA: 44.76000
• LogP: 2.60280

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 2,3-bis(2-propen-1-yloxy)-, methyl ester

There total 1 articles about Benzoic acid, 2,3-bis(2-propen-1-yloxy)-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

methyl-2,3-dihydroxybenzoate (2411-83-8) + allyl bromide (106-95-6) → methyl 2,3-bis(allyloxy)benzoate (919123-45-8)

Guidance literature:

With potassium carbonate; In acetonitrile; for 9.33333h; Heating / reflux;

Reference yield: 85.0%

methyl 2,3-bis(allyloxy)benzoate (919123-45-8) → 1-(2,3-bis(allyloxy)phenyl)-3-(morpholin-4-yl)propane-1,3-dione (919123-46-9)

Guidance literature:

4-acetylmorpholine; With lithium diisopropyl amide; In tetrahydrofuran; at -78 - 10 ℃; for 1.5h;

methyl 2,3-bis(allyloxy)benzoate; In tetrahydrofuran; at -78 - 20 ℃; for 2h;

With hydrogenchloride; water; In tetrahydrofuran; pH=1;

Reference yield: 85.0%

methyl 2,3-bis(allyloxy)benzoate (919123-45-8) + 4-acetylmorpholine (1696-20-4) → 1-(2,3-bis(allyloxy)phenyl)-3-(morpholin-4-yl)propane-1,3-dione (919123-46-9)

Guidance literature:

4-acetylmorpholine; With lithium diisopropyl amide; In tetrahydrofuran; at -78 - -10 ℃; for 1h;

methyl 2,3-bis(allyloxy)benzoate; In tetrahydrofuran; at -78 - 20 ℃; for 2h;

DOI:10.1021/ol062297x

upstream raw materials:

methyl-2,3-dihydroxybenzoate

allyl bromide

Downstream raw materials:

1-(2,3-bis(allyloxy)phenyl)-3-(morpholin-4-yl)propane-1,3-dione

1-(3-allyloxy-2-hydroxyphenyl)-3-(morpholin-4-yl)propane-1,3-dione

trifluoromethanesulfonic acid 2-(morpholin-4-yl)-4-oxo-4H-chromen-8-yl ester