4-Chloro-2,5-dimethylbenzenesulfonyl chloride

Base Information

• Chemical Name: 4-Chloro-2,5-dimethylbenzenesulfonyl chloride
• CAS No.: 88-49-3
• Molecular Formula: C8H8Cl2O2S
• Molecular Weight: 239.122
• Hs Code.: 2904909090
• European Community (EC) Number: 201-835-5
• UNII: FY2BCA5XT7
• DSSTox Substance ID: DTXSID80236749
• Nikkaji Number: J192.656J
• Wikidata: Q83118785
• Mol file: 88-49-3.mol

Synonyms:88-49-3;4-chloro-2,5-dimethylbenzenesulfonyl chloride;4-chloro-2,5-dimethylbenzene-1-sulfonyl chloride;5-Chloro-p-xylene-2-sulphonyl chloride;Benzenesulfonylchloride, 4-chloro-2,5-dimethyl-;EINECS 201-835-5;4-chloro-2,5-dimethylphenylsulfonyl chloride;Benzenesulfonyl chloride, 4-chloro-2,5-dimethyl-;4-Chloro-2,5-dimethylbenzenesulfonylchloride;FY2BCA5XT7;SCHEMBL152556;DTXSID80236749;5-chlor-p-xylen-2-sulfonylchlorid;AMY18954;BBL101838;MFCD00044017;STL555635;AKOS005139206;5-Chloro-p-xylene-2-sulfonyl chloride;2,5-Xylenesulfonyl chloride, 4-chloro-;AS-55112;4-chloro 2,5-dimethylphenylsulfonylchloride;FT-0618002;4-chloro-2,5-dimethyl-benzenesulfonyl chloride;EN300-271016;W16414;4-chloranyl-2,5-dimethyl-benzenesulfonyl chloride;A842625;W-109324;F1967-0205;4-chloro-2,5-dimethylbenzenesulfonyl chloride, AldrichCPR

Chemical Property of 4-Chloro-2,5-dimethylbenzenesulfonyl chloride

Chemical Property:

• Vapor Pressure: 0.000713mmHg at 25°C
• Melting Point: 48 °C
• Refractive Index: 1.551
• Boiling Point: 317.5 °C at 760 mmHg
• Flash Point: 145.8 °C
• PSA: 42.52000
• Density: 1.401g/cm³
• LogP: 3.96510
• Sensitive.: Moisture Sensitive
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 237.9622061
• Heavy Atom Count: 13
• Complexity: 270

Purity/Quality:

99% ^*data from raw suppliers

4-Chloro-2,5-dimethylbenzenesulfonyl chloride 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C； Xi
• Hazard Codes: Xi,C
• Statements: 34-36
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1Cl)C)S(=O)(=O)Cl

Technology Process of 4-Chloro-2,5-dimethylbenzenesulfonyl chloride

There total 5 articles about 4-Chloro-2,5-dimethylbenzenesulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 4-chloro-2,5-dimethylbenzene-1-sulfonyl chloride (88-49-3)

Guidance literature:

With phosphorus pentachloride; trichlorophosphate; at 110 ℃;

Reference yield:

→ 4-chloro-2,5-dimethylbenzene-1-sulfonyl chloride (88-49-3)

Guidance literature:

With phosphorus pentachloride; trichlorophosphate; at 110 ℃;

Reference yield:

4-Amino-2,5-dimethylbenzenesulfonic Acid (27897-08-1) → 4-chloro-2,5-dimethylbenzene-1-sulfonyl chloride (88-49-3)

Guidance literature:

DOI:10.1021/ja01320a040

upstream raw materials:

2-chloro-1,4-dimethyl-benzene

4-Amino-2,5-dimethylbenzenesulfonic Acid

Downstream raw materials:

methyl 3-[1-(4-chloro-2,5-dimethyl-phenylsulfonyl)-piperidin-2-yl]-propionate

N-((1-(3-(1-(4-chloro-2,5-dimethylphenylsulfonyl)piperidin-2-yl)propanoyl)-4-(4-methylpiperazin-1-yl)piperidin-4-yl)methyl)acetamide

3-[1-(4-chloro-2,5-dimethyl-phenylsulfonyl)-piperidin-2-yl]-propionic acid