1H-Isoindol-1-one, 2,3-dihydro-4,7-dihydroxy-2-methyl-

Base Information

• Chemical Name: 1H-Isoindol-1-one, 2,3-dihydro-4,7-dihydroxy-2-methyl-
• CAS No.: 919800-43-4
• Molecular Formula: C₉H₉NO₃
• Molecular Weight: 179.175

Synonyms:1H-Isoindol-1-one,2,3-dihydro-4,7-dihydroxy-2-methyl;4,7-dihydroxy-2-methyl-2,3-dihydro-1-isoindolone;

Chemical Property of 1H-Isoindol-1-one, 2,3-dihydro-4,7-dihydroxy-2-methyl-

Chemical Property:

• PSA: 60.77000
• LogP: 0.62130

Purity/Quality:

2,3-dihydro-4,7-dihydroxy-2-methyl-1H-Isoindol-1-one 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-Isoindol-1-one, 2,3-dihydro-4,7-dihydroxy-2-methyl-

There total 3 articles about 1H-Isoindol-1-one, 2,3-dihydro-4,7-dihydroxy-2-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

4,7-dihydroxy-2-methyl-2,3-dihydro-1-isoindoledione (132815-30-6) → 4,7-dihydroxy-2-methyl-2,3-dihydro-1-isoindolone (919800-43-4)

Guidance literature:

With hydrogenchloride; acetic acid; mercury; zinc; Heating;

DOI:10.1016/j.tet.2006.10.004

Reference yield:

2,3-dicyano-1,4-hydroquinone (4733-50-0) → 4,7-dihydroxy-2-methyl-2,3-dihydro-1-isoindolone (919800-43-4)

Guidance literature:

Multi-step reaction with 3 steps

1: KOH / H₂O / 3 h / Heating

2: 25 percent / dicyclohexylurea / tetrahydrofuran / 10 h / Heating

3: 30 percent / Zn(Hg); HCl; glacial AcOH / Heating

With hydrogenchloride; potassium hydroxide; N,N-dicyclohexylurea; acetic acid; mercury; zinc; In tetrahydrofuran; water; 3: Clemmensen reduction;

DOI:10.1016/j.tet.2006.10.004

Reference yield:

3,6-dihydroxyphthalic acid (3786-46-7) → 4,7-dihydroxy-2-methyl-2,3-dihydro-1-isoindolone (919800-43-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 25 percent / dicyclohexylurea / tetrahydrofuran / 10 h / Heating

2: 30 percent / Zn(Hg); HCl; glacial AcOH / Heating

With hydrogenchloride; N,N-dicyclohexylurea; acetic acid; mercury; zinc; In tetrahydrofuran; 2: Clemmensen reduction;

DOI:10.1016/j.tet.2006.10.004

upstream raw materials:

4,7-dihydroxy-2-methyl-2,3-dihydro-1-isoindoledione

2,3-dicyano-1,4-hydroquinone

3,6-dihydroxyphthalic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 919800-43-4 1H-Isoindol-1-one, 2,3-dihydro-4,7-dihydroxy-2-methyl-

Send

Send

Metric Ton KG G Pound L ML

Send

Send