Potassium (4-trifluoromethylphenyl)dimethylsilanolate

Base Information

• Chemical Name: Potassium (4-trifluoromethylphenyl)dimethylsilanolate
• CAS No.: 920015-51-6
• Molecular Formula: C9H11F3OSi.K
• Molecular Weight: 258.357
• Mol file: 920015-51-6.mol

Synonyms:

Chemical Property of Potassium (4-trifluoromethylphenyl)dimethylsilanolate

Chemical Property:

• Melting Point: 157.3-163.5°C
• PSA: 20.23000
• LogP: 2.22230

Purity/Quality:

99% ^*data from raw suppliers

Potassium (4-trifluoromethylphenyl)dimethylsilanolate 95% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Potassium (4-trifluoromethylphenyl)dimethylsilanolate

There total 1 articles about Potassium (4-trifluoromethylphenyl)dimethylsilanolate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

hydroxy(dimethyl)(4-trifluoromethylphenyl)silane (228873-97-0) → potassium (4-(trifluoromethyl)phenyl)dimethylsilanololate (920015-51-6)

Guidance literature:

With potassium hydride; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.1021/ja8091449

Reference yield: 78.0%

3-Bromopyridine (626-55-1,163928-56-1) + potassium (4-(trifluoromethyl)phenyl)dimethylsilanololate (920015-51-6) → 3-(4-trifluoromethyl-phenyl)-pyridine (426823-25-8)

Guidance literature:

With bis(tri-t-butylphosphine)palladium⁽⁰⁾; In toluene; at 90 ℃; Inert atmosphere;

DOI:10.1021/ja8091449

Reference yield: 58.0%

potassium (4-(trifluoromethyl)phenyl)dimethylsilanololate (920015-51-6) + 4-chlorobenzophenone (134-85-0) → phenyl[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methanone (1009026-35-0)

Guidance literature:

With bis(tri-t-butylphosphine)palladium⁽⁰⁾; In toluene; at 90 ℃; Inert atmosphere;

DOI:10.1021/ja8091449

upstream raw materials:

hydroxy(dimethyl)(4-trifluoromethylphenyl)silane

Downstream raw materials:

3-(4-trifluoromethyl-phenyl)-pyridine

phenyl[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methanone

4,4'-bis(trifluoromethyl)biphenyl

Refernces