Technology Process of 2(3H)-Furanone,
5-(3-buten-1-yl)dihydro-3-(phenylthio)-4-(2-propen-1-yl)-, (3S,4R,5R)-
There total 9 articles about 2(3H)-Furanone,
5-(3-buten-1-yl)dihydro-3-(phenylthio)-4-(2-propen-1-yl)-, (3S,4R,5R)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(3S,4R,5R)-4-allyl-5-(3-hydroxypropyl)-3-phenylthio-dihydrofuran-2-one;
With
pyridine-SO3 complex;
In
dichloromethane;
Methyltriphenylphosphonium bromide;
With
potassium hexamethylsilazane;
In
tetrahydrofuran;
DOI:10.1016/j.jorganchem.2006.08.021
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: SO3*pyridine / CH2Cl2
1.2: 78 percent / KHMDS / tetrahydrofuran
2.1: 92 percent / tetra-butylammonium fluoride / tetrahydrofuran / 20 °C
3.1: SO3*pyridine / CH2Cl2
3.2: 80 percent / KHDMS / tetrahydrofuran
With
pyridine-SO3 complex; tetrabutyl ammonium fluoride;
In
tetrahydrofuran; dichloromethane;
DOI:10.1016/j.jorganchem.2006.08.021
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: NaIO4; tetrabutylammonium periodate / methanol; H2O / 1 h / 20 °C
1.2: 74 percent / sodium hydride / benzene / 0.5 h
2.1: 95 percent / sodium hydride / dimethylformamide / 4 h
3.1: 90 percent / NaOH / tetrahydrofuran; H2O
4.1: 86 percent / BH3*SMe2 / tetrahydrofuran
5.1: SO3*pyridine / CH2Cl2
5.2: 78 percent / KHMDS / tetrahydrofuran
6.1: 92 percent / tetra-butylammonium fluoride / tetrahydrofuran / 20 °C
7.1: SO3*pyridine / CH2Cl2
7.2: 80 percent / KHDMS / tetrahydrofuran
With
sodium hydroxide; sodium periodate; pyridine-SO3 complex; dimethylsulfide borane complex; tetrabutyl ammonium fluoride; sodium hydride; tetrabutylammonium periodite;
In
tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/j.jorganchem.2006.08.021
