Benzamide, 3-[2-[(aminoiminomethyl)amino]-4-thiazolyl]-, monohydrobromide

Base Information

• Chemical Name: Benzamide, 3-[2-[(aminoiminomethyl)amino]-4-thiazolyl]-, monohydrobromide
• CAS No.: 92132-78-0
• Molecular Formula: BrH*C₁₁H₁₁N₅OS
• Molecular Weight: 342.219
• Mol file: 92132-78-0.mol

Synonyms:

Chemical Property of Benzamide, 3-[2-[(aminoiminomethyl)amino]-4-thiazolyl]-, monohydrobromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzamide, 3-[2-[(aminoiminomethyl)amino]-4-thiazolyl]-, monohydrobromide

There total 3 articles about Benzamide, 3-[2-[(aminoiminomethyl)amino]-4-thiazolyl]-, monohydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-hydroxy-1-butanitrile (628-22-8) + amidinothiocarbamide (2114-02-5) + 3-(bromoacetyl)benzenecarboxamide (92132-77-9) → 3-[2-[(Aminoiminomethyl)Amino]-4-Thiazolyl]Benzenecarboxamide, Hydrobromide (92132-78-0)

Guidance literature:

In water;

Reference yield:

3-acethylbenzonitrile (6136-68-1) → 3-<2-<(aminoiminomethyl)amino>-4-thiazolyl>benzenecarboxamide hydrobromide (92132-78-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 75 percent / HCl / toluene / 2 h

2: glacial acetic acid, Br₂ / 1 h

3: 36 percent / acetonitrile; ethanol / 0.08 h / Heating

With hydrogenchloride; bromine; acetic acid; In ethanol; toluene; acetonitrile;

DOI:10.1002/jhet.5570280839

Reference yield:

3-acetylbenzenecarboximidimic acid ethyl ester hydrochloride (60694-93-1) → 3-<2-<(aminoiminomethyl)amino>-4-thiazolyl>benzenecarboxamide hydrobromide (92132-78-0)

Guidance literature:

Multi-step reaction with 2 steps

1: glacial acetic acid, Br₂ / 1 h

2: 36 percent / acetonitrile; ethanol / 0.08 h / Heating

With bromine; acetic acid; In ethanol; acetonitrile;

DOI:10.1002/jhet.5570280839

upstream raw materials:

3-acethylbenzonitrile

3-acetylbenzenecarboximidimic acid ethyl ester hydrochloride

4-hydroxy-1-butanitrile

amidinothiocarbamide