6136-68-1Relevant articles and documents
Photoinduced Acetylation of Anilines under Aqueous and Catalyst-Free Conditions
Yang, Yu-Ming,Yan, Wei,Hu, Han-Wei,Luo, Yimin,Tang, Zhen-Yu,Luo, Zhuangzhu
, p. 12344 - 12353 (2021/09/02)
A green and efficient visible-light induced functionalization of anilines under mild conditions has been reported. Utilizing nontoxic, cost-effective, and water-soluble diacetyl as photosensitizer and acetylating reagent, and water as the solvent, a variety of anilines were converted into the corresponding aryl ketones, iodides, and bromides. With advantages of environmentally friendly conditions, simple operation, broad substrate scope, and functional group tolerance, this reaction represents a valuable method in organic synthesis.
Synthesis method of aromatic benzyl ketone
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Paragraph 0056-0061, (2020/09/12)
The invention discloses a synthesis method of aromatic benzyl ketone, which comprises the following step: by using oxygen and/or air as an oxidant, oxidizing an aromatic benzyl compound shown in a formula (I) under the action of a catalytic system to obtain aromatic benzyl ketone shown in a formula (II). The catalytic system is formed by combining ferric ions, nitrate radicals and N-hydroxyimide derivatives and does not contain heavy metal ions harmful to human bodies, wherein the molar ratio of the ferric ions to the nitrate radicals is 1: (0.5-5), and the molar ratio of the ferric ions to the N-hydroxyimide derivatives is (0.01-0.1): (0.03-0.2). The method disclosed by the invention is wide in substrate applicability and high in atom utilization rate, avoids the use of harmful heavy metals such as copper and cobalt, and has the characteristics of high efficiency, economy and environmental protection. The formulas are as follows: Ar-CH2-R (I) and Ar-CO-R (II).
Pd(II)-Catalyzed Denitrogenative and Desulfinative Addition of Arylsulfonyl Hydrazides with Nitriles
Meng, Mengting,Yang, Liangfeng,Cheng, Kai,Qi, Chenze
, p. 3275 - 3284 (2018/03/25)
A Pd(II)-catalyzed denitrogenative and desulfinative addition of arylsulfonyl hydrazides with nitriles has been successfully achieved under mild conditions. This transformation is a new method for the addition reaction to nitriles with arylsulfonyl hydrazides as arylating agent, thus providing an alternative synthesis of aryl ketones. The reported addition reaction is tolerant to many common functional groups, and works well in the presence of electron-donating and electron-withdrawing substituents. Notably, the reported denitrogenative and desulfinative addition was also appropriate for alkyl nitriles, making this newly developed transformation attractive.