Technology Process of Phosphoric acid, 2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethyl]phenyl
bis(phenylmethyl) ester
There total 9 articles about Phosphoric acid, 2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethyl]phenyl
bis(phenylmethyl) ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrachloromethane; N-ethyl-N,N-diisopropylamine;
dmap;
In
acetonitrile;
at -25 - -10 ℃;
for 1.1h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: hydrogen / 5%-palladium/activated carbon / ethanol; ethyl acetate / 1 h / 20 °C
2: tetrachloromethane; N-ethyl-N,N-diisopropylamine / dmap / acetonitrile / 1.1 h / -25 - -10 °C
With
tetrachloromethane; hydrogen; N-ethyl-N,N-diisopropylamine;
dmap; 5%-palladium/activated carbon;
In
ethanol; ethyl acetate; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: phosphorus tribromide / dichloromethane / 0.83 h / 20 °C
2: toluene / 1 h / Heating / reflux
3: potassium tert-butylate / tetrahydrofuran / 0.42 h / 20 °C
4: hydrogen / 5%-palladium/activated carbon / ethanol; ethyl acetate / 1 h / 20 °C
5: tetrachloromethane; N-ethyl-N,N-diisopropylamine / dmap / acetonitrile / 1.1 h / -25 - -10 °C
With
tetrachloromethane; potassium tert-butylate; hydrogen; phosphorus tribromide; N-ethyl-N,N-diisopropylamine;
dmap; 5%-palladium/activated carbon;
In
tetrahydrofuran; ethanol; dichloromethane; ethyl acetate; toluene; acetonitrile;
