N-{4-[2-(4-bromophenoxy)acetamido]phenyl}-3-chlorobenzamide

Base Information

Chemical Name:N-{4-[2-(4-bromophenoxy)acetamido]phenyl}-3-chlorobenzamide
CAS No.:5848-04-4
Molecular Formula:C21H16BrClN2O3
Molecular Weight:177.1783
Hs Code.:
DSSTox Substance ID:DTXSID50974025
Wikidata:Q82958154

Synonyms:Oprea1_580690;DTXSID50974025;N-{4-[2-(4-bromophenoxy)acetamido]phenyl}-3-chlorobenzamide

Suppliers and Price of N-{4-[2-(4-bromophenoxy)acetamido]phenyl}-3-chlorobenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of N-{4-[2-(4-bromophenoxy)acetamido]phenyl}-3-chlorobenzamide

Chemical Property:

Vapor Pressure:2.98E-06mmHg at 25°C
Boiling Point:388.8°Cat760mmHg
Flash Point:189°C
Density:1.334g/cm³
XLogP3:5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:458.00328
Heavy Atom Count:28
Complexity:520

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)Cl)C(=O)NC2=CC=C(C=C2)NC(=O)COC3=CC=C(C=C3)Br

Technology Process of N-{4-[2-(4-bromophenoxy)acetamido]phenyl}-3-chlorobenzamide

There total 2 articles about N-{4-[2-(4-bromophenoxy)acetamido]phenyl}-3-chlorobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 398-42-5
2-formyl-2-(4-fluorophenyl) acetonitrile

: 5848-04-4
3-amino-4-(4-fluorophenyl)-1H-pyrazole

Guidance literature:: With hydrazine; In acetic acid; toluene;
DOI:10.1002/(SICI)1521-4184(19996)332:6<219::AID-ARDP219>3.0.CO;2-T

Reference yield:

: 459-22-3
4-fluorophenylacetonitrile

: 5848-04-4
3-amino-4-(4-fluorophenyl)-1H-pyrazole

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium ethanolate / ethanol / 0.08 h / 0 °C / Inert atmosphere

1.2: 1 h / 85 °C / Inert atmosphere

2.1: hydrazine hydrate; acetic acid / ethanol / 2 h / 85 °C / Inert atmosphere

With sodium ethanolate; hydrazine hydrate; acetic acid; In ethanol;
DOI:10.1021/acsmedchemlett.1c00216