1,2-Cyclohexanediamine,N,N'-bis(2-pyridinylmethylene)-, (1R,2S)-rel- (9CI)

Base Information

• Chemical Name: 1,2-Cyclohexanediamine,N,N'-bis(2-pyridinylmethylene)-, (1R,2S)-rel- (9CI)
• CAS No.: 90605-88-2
• Molecular Formula: C18H20 N4
• Molecular Weight: 292.3782
• Mol file: 90605-88-2.mol

Synonyms:1,2-Cyclohexanediamine,N,N'-bis(2-pyridinylmethylene)-, cis-; NSC 351354;cis-1,2-Bis[(2-pyridinylmethylene)amino]cyclohexane

Chemical Property of 1,2-Cyclohexanediamine,N,N'-bis(2-pyridinylmethylene)-, (1R,2S)-rel- (9CI)

Chemical Property:

• Boiling Point: 485.2°Cat760mmHg
• Flash Point: 247.2°C
• Density: 1.14g/cm³

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2-Cyclohexanediamine,N,N'-bis(2-pyridinylmethylene)-, (1R,2S)-rel- (9CI)

There total 1 articles about 1,2-Cyclohexanediamine,N,N'-bis(2-pyridinylmethylene)-, (1R,2S)-rel- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

pyridine-2-carbaldehyde (1121-60-4) + cis-cyclohexane-1,2-diamine (1436-59-5) → N,N′-bis(2-pyridylmethylidene)-1,2-cis-(R,S)-cyclohexanediamine (90605-88-2)

Guidance literature:

In diethyl ether; for 19h; Ambient temperature;

DOI:10.1021/ja00328a031

Reference yield: 86.0%

bis[dimethyl(μ-dimethylsulfide)platinum(II)] + N,N′-bis(2-pyridylmethylidene)-1,2-cis-(R,S)-cyclohexanediamine (90605-88-2) → R,S/S,R-[PtMe2(cis-C6H10(N=CH-2-C5H4N)(N=CH-2-C5H4N))]

Guidance literature:

In diethyl ether; stirred for 24 h; ppt. cptd. and washed with Et2O; elem. anal.;

DOI:10.1021/om0007769

Reference yield: 81.0%

N,N′-bis(2-pyridylmethylidene)-1,2-cis-(R,S)-cyclohexanediamine (90605-88-2) → (1S,2R)-N,N'-bis(2-pyridylmethyl)cyclohexane-1,2-diamine (110171-62-5)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 - 20 ℃; for 3h;

DOI:10.1016/j.ica.2011.12.042

upstream raw materials:

pyridine-2-carbaldehyde

cis-cyclohexane-1,2-diamine

Downstream raw materials:

(1S,2R)-N,N'-bis(2-pyridylmethyl)cyclohexane-1,2-diamine