(2S,3S,4R,5R)-5-[6-amino-2-(phenethylamino)purin-9-yl]-N-ethyl-3,4-dih ydroxy-oxolane-2-carboxamide

Base Information

Chemical Name:(2S,3S,4R,5R)-5-[6-amino-2-(phenethylamino)purin-9-yl]-N-ethyl-3,4-dih ydroxy-oxolane-2-carboxamide
CAS No.:120225-53-8
Molecular Formula:C20H25 N7 O4
Molecular Weight:427.46
Hs Code.:
Mol file:120225-53-8.mol

Synonyms:CGS21577

Suppliers and Price of (2S,3S,4R,5R)-5-[6-amino-2-(phenethylamino)purin-9-yl]-N-ethyl-3,4-dih ydroxy-oxolane-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2S,3S,4R,5R)-5-[6-amino-2-(phenethylamino)purin-9-yl]-N-ethyl-3,4-dih ydroxy-oxolane-2-carboxamide

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：160.44000
Density:1.59g/cm³
LogP:0.86350

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (2S,3S,4R,5R)-5-[6-amino-2-(phenethylamino)purin-9-yl]-N-ethyl-3,4-dih ydroxy-oxolane-2-carboxamide

There total 7 articles about (2S,3S,4R,5R)-5-[6-amino-2-(phenethylamino)purin-9-yl]-N-ethyl-3,4-dih ydroxy-oxolane-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 120225-77-6
2-(2-phenyl)ethylamino-2',3'-O-isopropylideneadenosine-5'-N-ethylcarboxamide

: 120225-53-8
CGS 21577

Guidance literature:: With hydrogenchloride; water; In acetonitrile; at 50 ℃; for 12h;
DOI:10.1021/jm300206u

Reference yield:

: 24639-06-3
((3aR,4R,6R,6aR)-6-(6-amino-2-chloro-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol

: 120225-53-8
CGS 21577

Guidance literature:: Multi-step reaction with 5 steps

1: 74 percent / aq. KOH, KMnO₄ / H₂O / 72 h

2: SOCl₂ / dimethylformamide / 2 h / 50 °C

3: CH₂Cl₂ / 1 h / Ambient temperature

4: 3 h / 130 °C

5: 1 N HCl / 1 h / 65 °C

With hydrogenchloride; potassium hydroxide; potassium permanganate; thionyl chloride; In dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/jm00169a015

Reference yield:

: 72209-19-9
2-chloro-2',3'-O-isopropylideneadenosine-5'-carboxylic acid

: 120225-53-8
CGS 21577

Guidance literature:: Multi-step reaction with 4 steps

1: SOCl₂ / dimethylformamide / 2 h / 50 °C

2: CH₂Cl₂ / 1 h / Ambient temperature

3: 3 h / 130 °C

4: 1 N HCl / 1 h / 65 °C

With hydrogenchloride; thionyl chloride; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm00169a015