4-Chloro-5-nitrobenzene-1,2-diamine

Base Information

Chemical Name:4-Chloro-5-nitrobenzene-1,2-diamine
CAS No.:67073-39-6
Molecular Formula:C6H6ClN3O2
Molecular Weight:187.586
Hs Code.:29215119
European Community (EC) Number:690-880-8
DSSTox Substance ID:DTXSID90420652
Wikidata:Q82231959
Mol file:67073-39-6.mol

Synonyms:4-chloro-5-nitrobenzene-1,2-diamine;67073-39-6;4-CHLORO-5-NITRO-O-PHENYLENEDIAMINE;4-chloro-5-nitro-1,2-benzenediamine;MFCD03427594;4-chloro-5-nitro-1,2-phenylenediamine;SCHEMBL1192850;DTXSID90420652;LOQLMWFVXRZASN-UHFFFAOYSA-N;AC6572;AKOS016007539;FS-5641;4-chloro-5-nitro-benzene-1,2-diamine;BP-12405;SY039040;CS-0111830;FT-0641101;A19045;EN300-343624

Suppliers and Price of 4-Chloro-5-nitrobenzene-1,2-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Oakwood
4-Chloro-5-nitrobenzene-1,2-diamine 98%
1g
$ 69.00

Crysdot
4-Chloro-5-nitrobenzene-1,2-diamine 95+%
25g
$ 644.00

Crysdot
4-Chloro-5-nitrobenzene-1,2-diamine 95+%
10g
$ 322.00

Chemenu
4-Chloro-5-nitro-o-phenylenediamine 95%
10g
$ 327.00

Chemenu
4-Chloro-5-nitro-o-phenylenediamine 95%
5g
$ 204.00

Chemenu
4-Chloro-5-nitro-o-phenylenediamine 95%
25g
$ 608.00

American Custom Chemicals Corporation
4-CHLORO-5-NITRO-O-PHENYLENEDIAMINE 95.00%
5MG
$ 496.88

Ambeed
4-Chloro-5-nitrobenzene-1,2-diamine 95%
5g
$ 460.00

Ambeed
4-Chloro-5-nitrobenzene-1,2-diamine 95%
1g
$ 132.00

Ambeed
4-Chloro-5-nitrobenzene-1,2-diamine 95%
250mg
$ 53.00

Total 14 raw suppliers

Chemical Property of 4-Chloro-5-nitrobenzene-1,2-diamine

Chemical Property:

Vapor Pressure:1.32E-08mmHg at 25°C
Melting Point:189-193 °C
Boiling Point:458.9°Cat760mmHg
PKA:1.46±0.10(Predicted)
Flash Point:231.3°C
Density:1.592g/cm³
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:187.0148541
Heavy Atom Count:12
Complexity:184

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-5-nitrobenzene-1,2-diamine 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 20/21/22
Safety Statements: 36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=CC(=C1[N+](=O)[O-])Cl)N)N
Uses 4-Chloro-5-nitro-1,2-benzenediamine is used in the preparation of purinone compounds as DNA-PK inhibitors for treating cancer.

Technology Process of 4-Chloro-5-nitrobenzene-1,2-diamine

There total 8 articles about 4-Chloro-5-nitrobenzene-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 113269-04-8
N-[4-chloro-5-nitro-2-(4-toluenesulfonylamino)-phenyl]-4-toluenesulfonamide

: 67073-39-6
4-nitro-5-chloro-1,2-phenylenediamine

Guidance literature:: With sulfuric acid; at 85 ℃; for 0.5h;
DOI:10.3987/R-1987-09-2433

Reference yield:

: 3698-83-7
2,4-dichloro-1,5-dinitrobenzene

: 67073-39-6
4-nitro-5-chloro-1,2-phenylenediamine

Guidance literature:: Multi-step reaction with 3 steps

1: NaN₃

2: propan-1-ol / Heating

3: aq. HI

With sodium azide; hydrogen iodide; In propan-1-ol;
DOI:10.1021/ja01494a030

Reference yield:

: 100245-74-7
1-azido-5-chloro-2,4-dinitro-benzene

: 67073-39-6
4-nitro-5-chloro-1,2-phenylenediamine

Guidance literature:: Multi-step reaction with 2 steps

1: propan-1-ol / Heating

2: aq. HI

With hydrogen iodide; In propan-1-ol;
DOI:10.1021/ja01494a030