3,7-Dimethylquinoxalin-6-amine

Base Information

Chemical Name:3,7-Dimethylquinoxalin-6-amine
CAS No.:122457-29-8
Molecular Formula:C₁₀H₁₁N₃
Molecular Weight:173.217
Hs Code.:
DSSTox Substance ID:DTXSID20558255
Wikidata:Q82440482
Mol file:122457-29-8.mol

Synonyms:3,7-DIMETHYLQUINOXALIN-6-AMINE;122457-29-8;6-Quinoxalinamine,3,7-dimethyl-(9CI);SCHEMBL21591884;DTXSID20558255

Suppliers and Price of 3,7-Dimethylquinoxalin-6-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3,7-Dimethylquinoxalin-6-amine

Chemical Property:

PSA：51.80000
LogP:2.41000
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:173.095297364
Heavy Atom Count:13
Complexity:183

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=NC=C(N=C2C=C1N)C

Technology Process of 3,7-Dimethylquinoxalin-6-amine

There total 6 articles about 3,7-Dimethylquinoxalin-6-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 122457-28-7
3,7-dimethyl-6-nitroquinoxaline

: 122457-29-8
3,7-dimethyl-6-aminoquinoxaline

Guidance literature:: With hydrogen; nickel; In ethanol; water; for 1h; under 760 Torr; Ambient temperature;
DOI:10.1016/0040-4020(89)80127-9

Reference yield:

: 823-96-1
Trimethylboroxine

: 67073-39-6
4-nitro-5-chloro-1,2-phenylenediamine

: 78-98-8
2-oxopropanal

: 2,7-dimethylquinoxalin-6-amine

: 122457-29-8
3,7-dimethyl-6-aminoquinoxaline

Guidance literature:: 4-nitro-5-chloro-1,2-phenylenediamine; 2-oxopropanal; With iron; ammonium chloride; In ethanol; at 17 - 25 ℃; for 1h; Reflux; Inert atmosphere;

Trimethylboroxine; With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate; In 1,4-dioxane; water; at 17 - 25 ℃; for 2h; Reflux; Inert atmosphere;

With iron; ammonium chloride; In ethanol; water; at 17 - 100 ℃; for 1h; Overall yield = 81 percent; Overall yield = 600 mg; Inert atmosphere;

Reference yield:

: 51676-74-5
1-chloro-5-methyl-2,4-dinitrobenzene

: 122457-29-8
3,7-dimethyl-6-aminoquinoxaline

Guidance literature:: Multi-step reaction with 4 steps

1: 89 percent / Et₃N / ethanol / 4 h / Heating

2: 65 percent / hydrazine hydrate / Raney-Ni / ethanol; 1,2-dichloro-ethane / 4 h / 60 °C

3: 78 percent / tetrakis(acetonitrile)copper(I) tetrafluoroborate / toluene / 20 h / 90 °C

4: 90 percent / H₂ / Raney-Ni / ethanol; H₂O / 1 h / 760 Torr / Ambient temperature

With hydrogen; tetrakis(acetonitrile)copper(I) tetrafluoroborate; hydrazine hydrate; triethylamine; nickel; In ethanol; water; 1,2-dichloro-ethane; toluene;
DOI:10.1016/0040-4020(89)80127-9