6-Chloroacetyl-1,4-benzodioxane

Base Information

Chemical Name:6-Chloroacetyl-1,4-benzodioxane
CAS No.:93439-37-3
Molecular Formula:C₁₀H₉ClO₃
Molecular Weight:212.633
Hs Code.:2932999099
European Community (EC) Number:625-427-5
DSSTox Substance ID:DTXSID70381636
Nikkaji Number:J1.729.076B
Wikidata:Q82172575
Mol file:93439-37-3.mol

Synonyms:6-Chloroacetyl-1,4-benzodioxane;93439-37-3;2-chloro-1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethanone;MFCD00099407;2-chloro-1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethan-1-one;2-chloro-1-(2,3-dihydrobenzo[b][1,4]dioxin-7-yl)ethanone;SCHEMBL1535157;DTXSID70381636;BBL010702;STK298913;AKOS000111887;FS-4133;6-Chloroacetyl-1,4-benzodioxane, 97%;CS-0270638;FT-0766779;2,3-Dihydro-6-(chloroacetyl)-1,4-benzodioxin;EN300-1982738;2-chloro-1-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-ethanone;2-chloro-1-(2,3-dihydrobenzo[1,4]dioxin-6-yl)-ethanone;2-chloro-1 -(2,3-dihydro-benzo[1,4]dioxin-6-yl)-ethanone;2-chloro-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)ethanone;2-Chloro-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)ethan-1-one

Suppliers and Price of 6-Chloroacetyl-1,4-benzodioxane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Chloroacetyl-1,4-benzodioxane
100mg
$ 75.00

Sigma-Aldrich
6-Chloroacetyl-1,4-benzodioxane 97%
25g
$ 337.00

Matrix Scientific
2-Chloro-1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethanone 95%
10g
$ 227.00

Matrix Scientific
2-Chloro-1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethanone 95%
1g
$ 66.00

Heterocyclics
2-Chloro-1-(2,3-dihydrobenzo[b][1,4]dioxin-7-yl)ethanone 97%
25g
$ 347.00

Heterocyclics
2-Chloro-1-(2,3-dihydrobenzo[b][1,4]dioxin-7-yl)ethanone 97%
5g
$ 112.00

Heterocyclics
2-Chloro-1-(2,3-dihydrobenzo[b][1,4]dioxin-7-yl)ethanone 97%
100g
$ 610.00

Crysdot
2-Chloro-1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethanone 95+%
100g
$ 503.00

Biosynth Carbosynth
6-Chloroacetyl-1,4-benzodioxane
50 g
$ 535.50

Biosynth Carbosynth
6-Chloroacetyl-1,4-benzodioxane
100 g
$ 857.00

Total 16 raw suppliers

Chemical Property of 6-Chloroacetyl-1,4-benzodioxane

Chemical Property:

Vapor Pressure:2.62E-05mmHg at 25°C
Melting Point:137-140oC(lit.)
Boiling Point:358oC at 760 mmHg
Flash Point:161.2oC
PSA：35.53000
Density:1.318g/cm3
LogP:1.87930
XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:212.0240218
Heavy Atom Count:14
Complexity:219

Purity/Quality:

99%, ^*data from raw suppliers

6-Chloroacetyl-1,4-benzodioxane ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC2=C(O1)C=CC(=C2)C(=O)CCl

Technology Process of 6-Chloroacetyl-1,4-benzodioxane

There total 2 articles about 6-Chloroacetyl-1,4-benzodioxane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 2879-20-1
1,4-benzodioxan-6-yl methyl ketone

: 93439-37-3
2-chloro-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)ethan-1-one

Guidance literature:: With hydrogenchloride; ammonium nitrate; iodine; oxygen; In water; acetonitrile; at 60 ℃; for 22h; regioselective reaction; Green chemistry;
DOI:10.1002/adsc.201301012

Reference yield:

: 493-09-4
benzo-1,4-dioxane

: 79-04-9
chloroacetyl chloride

: 93439-37-3
2-chloro-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)ethan-1-one

Guidance literature:: chloroacetyl chloride; With aluminum (III) chloride; In dichloromethane; at 10 - 20 ℃; for 0.25h; Inert atmosphere;

benzo-1,4-dioxane; In dichloromethane; at 10 - 20 ℃; for 1h;