2-Azaspiro[4.5]decane-3-carbonitrile

Base Information

Chemical Name:2-Azaspiro[4.5]decane-3-carbonitrile
CAS No.:93960-17-9
Molecular Formula:C₁₀H₁₆N₂
Molecular Weight:164.25
Hs Code.:
DSSTox Substance ID:DTXSID30529057
Mol file:93960-17-9.mol

Synonyms:2-Azaspiro[4.5]decane-3-carbonitrile;93960-17-9;SCHEMBL9733206;DTXSID30529057;CS-0458834

Suppliers and Price of 2-Azaspiro[4.5]decane-3-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Azaspiro[4.5]decane-3-carbonitrile

Chemical Property:

PSA：35.82000
LogP:2.15118
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:164.131348519
Heavy Atom Count:12
Complexity:207

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC2(CC1)CC(NC2)C#N

Technology Process of 2-Azaspiro[4.5]decane-3-carbonitrile

There total 5 articles about 2-Azaspiro[4.5]decane-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 93960-16-8
2-Aza-spiro[4.5]dec-2-ene

: 93960-17-9
spiro<4.5>-2-aza-decan-3-carbonitrile

Guidance literature:: In ethanol; acetic acid; at -10 ℃; for 5h;
DOI:10.1016/S0040-4039(01)81472-6

Reference yield:

: 766-05-2
cyclohexane carbonitrile

: 93960-17-9
spiro<4.5>-2-aza-decan-3-carbonitrile

Guidance literature:: Multi-step reaction with 4 steps

1: 80 percent / diethylamine, n-butyllithium / hexane / 24 h / -70 °C

2: 90 percent / sodium / ethanol

3: 1N HCl / ethanol / 1 h

4: aq. acetic acid; ethanol / 5 h / -10 °C

With hydrogenchloride; n-butyllithium; sodium; diethylamine; In ethanol; hexane; acetic acid;
DOI:10.1016/S0040-4039(01)81472-6

Reference yield:

: 88578-94-3
aminomethyl-di-(ethyloxy)ethyl-cyclohexane

: 93960-17-9
spiro<4.5>-2-aza-decan-3-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 1N HCl / ethanol / 1 h

2: aq. acetic acid; ethanol / 5 h / -10 °C

With hydrogenchloride; In ethanol; acetic acid;
DOI:10.1016/S0040-4039(01)81472-6